Lycium Barbarum L. (Goji Berry) fruits improve anxiety, depression-like behaviors, and learning performance: The moderating role of sex

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dc.authorid0000-0001-5245-6294
dc.authorid0000-0002-5509-8717
dc.contributor.authorKarakaş, Fatma Pehlivan
dc.contributor.authorCoşkun, Hamit
dc.contributor.authorSağlam, Kadir
dc.contributor.authorBozat, Bihter Gökçe
dc.date.accessioned2021-06-23T18:40:10Z
dc.date.available2021-06-23T18:40:10Z
dc.date.issued2016
dc.departmentBAİBÜ, Fen Edebiyat Fakültesi, Biyoloji Bölümüen_US
dc.departmentBAİBÜ, Fen Edebiyat Fakültesi, Psikoloji Bölümü
dc.departmentBAİBÜ, Lisansüstü Eğitim Enstitüsü, Fen Bilimleri, Biyoloji Ana Bilim Dalı
dc.description.abstractThe aim of this research was to investigate the effects of the methanol extract obtained from Lycium barbarum fruits on anxiety, depression-like behaviors, and spatial memory in Wistar albino rats. A total of 28 rats were selected, randomly assigned to four experimental groups, and tested by means of the open field and elevated plus maze tests for anxiety-like behaviors, the forced swim test for depression-like behaviors, and the Morris water maze test for spatial memory. The findings demonstrated that in the open field, L. Barbarum-administered rats spent more time at the center and showed more mobility and velocity than controls. In the elevated plus maze, L. Barbarum-administered rats spent more time in the open arms, spent less time in the closed arms, and showed more mobility and velocity. In the Porsolt test, L. Barbarum-administered rats showed less immobility. In the Morris water maze, L. Barbarum-administered rats took more time to find the platform. However, females were better at finding the platform than males. The methanol extract of L. Barbarum fruits decreased anxiety and depression-like behaviors and interacted with sex on spatial memory.en_US
dc.identifier.endpage771en_US
dc.identifier.issn1300-0152
dc.identifier.issn1303-6092
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-84975318416en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage762en_US
dc.identifier.trdizinid214730en_US
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TWpFME56TXdNQT09
dc.identifier.urihttps://hdl.handle.net/20.500.12491/2998
dc.identifier.volume40en_US
dc.identifier.wosWOS:000378689600006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorKarakaş, Fatma Pehlivan
dc.institutionauthorCoşkun, Hamit
dc.institutionauthorSağlam, Kadir
dc.institutionauthorBozat, Bihter Gökçe
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectLycium Barbarum (Goji Berry)en_US
dc.subjectAnxiety
dc.subjectDepression
dc.subjectSpatial Memory
dc.subjectWistar Albino Rat (Rattus Rattus)
dc.titleLycium Barbarum L. (Goji Berry) fruits improve anxiety, depression-like behaviors, and learning performance: The moderating role of sexen_US
dc.typeArticleen_US

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