Cardiac findings in Behcet's patients

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dc.authorid0000-0001-9226-5134
dc.contributor.authorHeper, Gülümser
dc.contributor.authorPolat, Mualla
dc.contributor.authorYetkin, Ertan
dc.contributor.authorŞenen, Kubilay
dc.date.accessioned2021-06-23T19:27:01Z
dc.date.available2021-06-23T19:27:01Z
dc.date.issued2010
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractBehcet's disease is a chronic multi-system inflammatory disorder and the severity and clinical manifestations of Behcet's patients may show geographic variation. We aimed to detect the cardiac findings in 30 Behcet's patients and compare them with the normal population (n = 29). We used color-doppler echocardiography and transesophageal echocardiography in combination. We calculated manually QT intervals and QT dispersion (QTd) from twelve-lead ECG recordings. There was no E/A inversion and coronary ischemia in all patients or control group. The E velocity difference between groups was not significant. The mean A velocity was significantly lower in Behcet's patients than normal group. The mean DT was 154.4 +/- 5.8 msec in Behcet's patients and 122.59 +/- 0.96 msec in control group (P < 0.0001). The mean IVRT was 75.66 +/- 1.36 msec in Behcet's patients and 69.1 +/- 0.55 msec in control group (P < 0.0001). There was no QTc time difference between the Behcet's patients and the control group. The mean QT dispersion (QTd) interval was 45.46 +/- 2.65 msec in Behcet's patients and 31.83 +/- 1.23 msec in control group (P < 0.0001). Atrial septal aneurysm, mitral valve prolapse and insufficiency, tricuspid valve insufficieny, and pulmonary hypertension frequencies in Behcet's patients were significantly higher than in the control group. We concluded that Behcet's cardiac involvement may effect cardiac structure and cause diastolic dysfunction, electrical instability and structural abnormalities. We also concluded that cardiac involvement in Behcet's disease may be specific for this geographic area.en_US
dc.identifier.doi10.1111/j.1365-4632.2010.04424.x
dc.identifier.endpage578en_US
dc.identifier.issn0011-9059
dc.identifier.issn1365-4632
dc.identifier.issue5en_US
dc.identifier.pmid20534096en_US
dc.identifier.scopus2-s2.0-77953088861en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage574en_US
dc.identifier.urihttps://doi.org/10.1111/j.1365-4632.2010.04424.x
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6715
dc.identifier.volume49en_US
dc.identifier.wosWOS:000276935400019en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorHeper, Gülümser
dc.institutionauthorPolat, Mualla
dc.institutionauthorYetkin, Ertan
dc.institutionauthorŞenen, Kubilay
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofInternational Journal Of Dermatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBehcet's patientsen_US
dc.titleCardiac findings in Behcet's patientsen_US
dc.typeArticleen_US

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