Platelet-rich plasma for skin graft storage an experimental study using rabbit ears

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dc.authorid0000-0001-9077-2976
dc.authorid0000-0002-6553-4500
dc.contributor.authorGökkaya, Ali
dc.contributor.authorGörgü, Metin
dc.contributor.authorKızılkan, Jehat
dc.contributor.authorKaranfil, Ertuğrul
dc.contributor.authorDoğan, Ali
dc.contributor.authorAstarcı, Hesna Müzeyyen
dc.date.accessioned2021-06-23T19:54:06Z
dc.date.available2021-06-23T19:54:06Z
dc.date.issued2020
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground Storage of surplus grafts for later use is one of the standard procedures used in plastic surgery. For the delayed use of skin grafts, various methods and media have been investigated for short-term storage. This study aimed to investigate the effect of platelet-rich plasma (PRP) skin graft storage on the survival of skin grafts obtained from rabbit ears. Materials and Methods Twelve rabbits were used in this study. A total of 12 skin grafts measuring 1 x 1 cm(2)were obtained from the inner surfaces of the rabbits' ears. The grafts were stored at +4 degrees C in saline, Hartmann's, and PRP media. On days 3, 7, 10, and 14, the grafts were implanted into the ears in areas measuring 1 x 1 cm(2)where the skin, cartilage, and perichondria were excised. After the implantation of the grafts, the survival rates were evaluated by measuring the graft areas on day 0, day 10, and day 30. Results The graft survival rate decreased as the storage period increased in all 3 of the media. The decrease in survival rate was higher in the grafts that were stored in the Hartmann's media in comparison with the saline and PRP media, and the difference was statistically significant. The decrease in graft survival was similar between the storage in saline and PRP media; however, the differences were statistically insignificant. Conclusions Although in vitro criteria are important for evaluating graft survival, in vivo studies showing the graft take rate in the recipient area are required. When the in vivo criteria are evaluated, the use of PRP is not superior to the use of saline for graft storage. However, additional studies are required to evaluate the effects of PRP media on graft quality.en_US
dc.identifier.doi10.1097/SAP.0000000000002253
dc.identifier.endpage75en_US
dc.identifier.issn0148-7043
dc.identifier.issn1536-3708
dc.identifier.issue1en_US
dc.identifier.pmid32032121en_US
dc.identifier.scopus2-s2.0-85086522698en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage68en_US
dc.identifier.urihttps://doi.org/10.1097/SAP.0000000000002253
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10420
dc.identifier.volume85en_US
dc.identifier.wosWOS:000552995600013en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorGökkaya, Ali
dc.institutionauthorGörgü, Metin
dc.institutionauthorKızılkan, Jehat
dc.institutionauthorKaranfil, Ertuğrul
dc.institutionauthorDoğan, Ali
dc.institutionauthorAstarcı, Hesna Müzeyyen
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofAnnals Of Plastic Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSkin Graften_US
dc.subjectStorageen_US
dc.subjectPreservationen_US
dc.subjectPlatelet-rich Plasmaen_US
dc.subjectRabbit Earsen_US
dc.subjectSecondary Contractionen_US
dc.titlePlatelet-rich plasma for skin graft storage an experimental study using rabbit earsen_US
dc.typeArticleen_US

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