Platelet-rich plasma for skin graft storage an experimental study using rabbit ears
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Dosyalar
Tarih
2020
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Lippincott Williams & Wilkins
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background Storage of surplus grafts for later use is one of the standard procedures used in plastic surgery. For the delayed use of skin grafts, various methods and media have been investigated for short-term storage. This study aimed to investigate the effect of platelet-rich plasma (PRP) skin graft storage on the survival of skin grafts obtained from rabbit ears. Materials and Methods Twelve rabbits were used in this study. A total of 12 skin grafts measuring 1 x 1 cm(2)were obtained from the inner surfaces of the rabbits' ears. The grafts were stored at +4 degrees C in saline, Hartmann's, and PRP media. On days 3, 7, 10, and 14, the grafts were implanted into the ears in areas measuring 1 x 1 cm(2)where the skin, cartilage, and perichondria were excised. After the implantation of the grafts, the survival rates were evaluated by measuring the graft areas on day 0, day 10, and day 30. Results The graft survival rate decreased as the storage period increased in all 3 of the media. The decrease in survival rate was higher in the grafts that were stored in the Hartmann's media in comparison with the saline and PRP media, and the difference was statistically significant. The decrease in graft survival was similar between the storage in saline and PRP media; however, the differences were statistically insignificant. Conclusions Although in vitro criteria are important for evaluating graft survival, in vivo studies showing the graft take rate in the recipient area are required. When the in vivo criteria are evaluated, the use of PRP is not superior to the use of saline for graft storage. However, additional studies are required to evaluate the effects of PRP media on graft quality.
Açıklama
Anahtar Kelimeler
Skin Graft, Storage, Preservation, Platelet-rich Plasma, Rabbit Ears, Secondary Contraction
Kaynak
Annals Of Plastic Surgery
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
85
Sayı
1
