Bone mineral density measurements in otosclerosis using dual-energy X-ray absorptiometry

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dc.authorid0000-0003-0290-9341en_US
dc.authorid0000-0002-4646-7250
dc.contributor.authorTönük, Şükrü Burak
dc.contributor.authorKöybaşı, Serap
dc.contributor.authorBiçer, Yusuf Özgür
dc.contributor.authorAlkan Temel, Sema
dc.date.accessioned2021-06-23T19:43:43Z
dc.date.available2021-06-23T19:43:43Z
dc.date.issued2016
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.description.abstractObjectivesThis study aims to evaluate patients with otosclerosis with respect to bone mineral density (BMD) at different regions of interest (ROI), using dual-energy X-ray absorptiometry (DXA). DesignCross-sectional controlled study. SettingTertiary referral hospital. ParticipantsThe patients with a definite diagnosis of otosclerosis confirmed intra-operatively were defined as the study group (n=30). The control group consisted of volunteer, healthy subjects with normal hearing (n=43). Main outcome measuresFollowing an audiometric evaluation, a venous blood sample was obtained and a single BMD measurement using DXA was applied to each participant. ResultsThe mean BMD, T and Z scores were higher in the otosclerosis group than in the control group in all the regions considered, but not significantly; only the L2-L3 lateral BMD and its T and Z scores were significant (P=0.036, P=0.029 and P=0.036, respectively). ConclusionThis study shows that the BMD does not decrease in the presence of otosclerosis despite its genetic and metabolic relevance with osteoporosis. Concerning the L2-L3 lateral BMD measurements, the BMD increased in otosclerosis.en_US
dc.identifier.doi10.1111/coa.12486
dc.identifier.endpage153en_US
dc.identifier.issn1749-4478
dc.identifier.issn1749-4486
dc.identifier.issue2en_US
dc.identifier.pmid26096174en_US
dc.identifier.scopus2-s2.0-84959358093en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage149en_US
dc.identifier.urihttps://doi.org/10.1111/coa.12486
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8836
dc.identifier.volume41en_US
dc.identifier.wosWOS:000372306200006en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorTönük, Şükrü Burak
dc.institutionauthorKöybaşı, Serap
dc.institutionauthorBiçer, Yusuf Özgür
dc.institutionauthorAlkan Temel, Sema
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofClinical Otolaryngologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDual-Energy X-Rayabsorptiometry (DXA)en_US
dc.subjectBone Mineral Density (BMD)
dc.subjectL2-L3 Lateral BMDand
dc.subject(n=30)
dc.titleBone mineral density measurements in otosclerosis using dual-energy X-ray absorptiometryen_US
dc.typeArticleen_US

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