Red cell distribution width and mean platelet volume in patients with irritable bowel syndrome

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dc.authorid0000-0001-7306-5233
dc.authorid0000-0002-3156-1076
dc.authorid0000-0002-5924-7476
dc.authorid0000-0002-7475-7298
dc.authorid0000-0002-7422-1442
dc.contributor.authorAktaş, Gülali
dc.contributor.authorAlçelik, Aytekin
dc.contributor.authorTekçe, Buket Kin
dc.contributor.authorTekelioğlu, Vildan
dc.contributor.authorŞit, Mustafa
dc.contributor.authorŞavlı, Haluk
dc.date.accessioned2021-06-23T18:55:20Z
dc.date.available2021-06-23T18:55:20Z
dc.date.issued2014
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractIntroduction: Possible pathophysiological mechanisms of irritable bowel syndrome (IBS) are interactions between microbial flora of the gut and the mucosal/systemic immune system, post-infectious status and inflammation. Mean platelet volume (MPV) and red cell distribution width (RDW) have been reported as inflammatory markers in patients with inflammatory bowel disease, but they have not been studied in functional gastrointestinal disorders. Aim: To investigate whether there was an association between haemogram parameters (RDW and MPV) and IBS. Material and methods: Forty patients with IBS and 44 healthy controls were included to this retrospective study. Patients diagnosed with IBS according to Rome III criteria were included as the IBS group. They were all screened for psychiatric or organic bowel diseases for the sake of precise diagnosis. Results: Both RDW (p < 0.001) and MPV (p = 0.046) were increased in patients with IBS compared to controls. This increase in RDW and MPV was independent of the type of IBS. Conclusions: The RDW and MPV should be laboratory indicators of IBS. More prospective studies with larger cohorts are needed to confirm our results.en_US
dc.identifier.doi10.5114/pg.2014.43578
dc.identifier.endpage163en_US
dc.identifier.issn1895-5770
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84904011404en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage160en_US
dc.identifier.urihttps://doi.org/10.5114/pg.2014.43578
dc.identifier.urihttps://hdl.handle.net/20.500.12491/4745
dc.identifier.volume9en_US
dc.identifier.wosWOS:000216155000007en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorAktaş, Gülali
dc.institutionauthorAlçelik, Aytekin
dc.institutionauthorTekçe, Buket Kin
dc.institutionauthorTekelioğlu, Vildan
dc.institutionauthorŞit, Mustafa
dc.institutionauthorŞavlı, Haluk
dc.language.isoenen_US
dc.publisherTermedia Publishing House Ltd.en_US
dc.relation.ispartofPrzeglad Gastroenterologicznyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectInflammationen_US
dc.subjectIrritable Bowel Syndromeen_US
dc.subjectMean Platelet Volumeen_US
dc.subjectRed Cell Distribution Widthen_US
dc.titleRed cell distribution width and mean platelet volume in patients with irritable bowel syndromeen_US
dc.typeArticleen_US

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