Thyroid autoimmunity in patients with Familial Mediterranean Fever: preliminary results

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dc.authorid0000-0002-3613-0523en_US
dc.authorid0000-0003-1710-7018en_US
dc.authorid0000-0002-4060-3354en_US
dc.contributor.authorDikbaş, Oğuz
dc.contributor.authorSoy, Mehmet
dc.contributor.authorBes, C.
dc.contributor.authorAnkaralı, H.
dc.contributor.authorBuğdaycı, Güler
dc.contributor.authorZeyrek, Ahsen
dc.date.accessioned2021-06-23T19:34:09Z
dc.date.available2021-06-23T19:34:09Z
dc.date.issued2013
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractAIM: We investigated whether there was a significant increase in thyroid autoimmunity in patients with Familial Mediterranean fever (FMF). PATIENTS AND METHODS: In total, 220 patients, consisting of 42 with FMF, 75 with rheumatoid arthritis (RA), and 103 healthy controls, were enrolled. Serum thyroid-stimulating hormone (TSH), free triiodothyronine (fT3), free thyroxine (fT4), and thyroid autoantibodies (anti-thyroid peroxidase and anti-thyroglobulin) were measured in all participants. RESULTS: After adjustment for age, gender, and smoking status, statistically significant differences between serum levels of anti-thyroglobulin antibody, anti-thyroid peroxidase antibody, and fT3 were found between the groups (all p < 0.001). Serum TSH level did not differ between the groups (p > 0.05). The frequency of autoimmune thyroiditis in FMF group is higher than control group. However, this difference did not reached the level of statistical significance (p > 0.05). CONCLUSIONS: Although statistically not significant, thyroid autoimmunity was observed more frequently in patients with FMF than in healthy controls. Thyroid autoantibodies were significantly higher in patients with FMF. Studies with greater number of patients are required for evaluating the frequency of the autoimmune thyroiditis in patients with FMF.en_US
dc.identifier.endpage3030en_US
dc.identifier.issn1128-3602
dc.identifier.issue22en_US
dc.identifier.pmid24302182en_US
dc.identifier.scopus2-s2.0-84891771398en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage3024en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7403
dc.identifier.volume17en_US
dc.identifier.wosWOS:000328085300008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorSoy, Mehmet
dc.institutionauthorBes, C.
dc.institutionauthorBuğdaycı, Güler
dc.institutionauthorZeyrek, Ahsen
dc.institutionauthorDikbaş, Oğuz
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical And Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAutoimmuneen_US
dc.subjectThyroiden_US
dc.subjectFamilial Mediterranean Feveren_US
dc.subjectRheumatoid Artritisen_US
dc.titleThyroid autoimmunity in patients with Familial Mediterranean Fever: preliminary resultsen_US
dc.typeArticleen_US

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