The effect of astaxanthin on human sperm parameters after cryopreservation

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dc.authorid0000-0002-1065-3254en_US
dc.contributor.authorDede, Gizem
dc.contributor.authorSaylan, Aslıhan
dc.date.accessioned2024-03-14T08:45:46Z
dc.date.available2024-03-14T08:45:46Z
dc.date.issued2022en_US
dc.departmentBAİBÜ, Lisansüstü Eğitim Enstitüsü, Sağlık Bilimleri, Histoloji ve Embriyoloji Ana Bilim Dalıen_US
dc.description.abstractIntroduction: The aim of the study was to examine the protecti-ve efficacy of astaxanthin (ASTA) against the damage that occurs during sperm cryopreservation.Methods: This experimental study was carried out on waste semen samples of 30 normozoospermic individuals who applied for semen analysis. Semen samples were divided into four equal volumes and 0 pM (control group), 50 pM, 100 pM, and 500 pM ASTA were added to each group. All groups were stored frozen in a liquid nitrogen tank. Semen samples were removed from liquid nitrogen after 72 hours and were thawed. Motility evaluation of sperm was performed. In addition, sperm was stained with acidic aniline blue to detect DNA chromatin condensation.Results: The highest motility loss was found in the control group and the least motility loss was in the 100 pM ASTA group. When examined in terms of sperm chromatin condensation, condensed sperm count was higher in the 100 pM ASTA group than in the other groups.Conclusions: It has been observed that ASTA added to the cryopro-tectant substance during sperm cryopreservation positively affects sperm motility and reduces the number of decondensed sperm.en_US
dc.identifier.citationDede, G., & Saylan, A. (2022). The effect of astaxanthin on human sperm parameters after cryopreservation. Canadian Urological Association Journal, 16(11), E552.en_US
dc.identifier.doi10.5489/cuaj.7876
dc.identifier.endpageE557en_US
dc.identifier.issn1920-1214
dc.identifier.issue11en_US
dc.identifier.pmid35704936en_US
dc.identifier.scopus2-s2.0-85133062832en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpageE552en_US
dc.identifier.urihttp://dx.doi.org/10.5489/cuaj.7876
dc.identifier.urihttps://hdl.handle.net/20.500.12491/12086
dc.identifier.volume16en_US
dc.identifier.wosWOS:000882962100008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorDede, Gizem
dc.institutionauthorSaylan, Aslıhan
dc.language.isoenen_US
dc.publisherCanadian Urological Associationen_US
dc.relation.ispartofCUAJ-Canadian Urological Association Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - İdari Personel ve Öğrencien_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectOxidative Stressen_US
dc.subjectSpermatozoaen_US
dc.subjectMorphologyen_US
dc.subjectQualityen_US
dc.subjectCellsen_US
dc.titleThe effect of astaxanthin on human sperm parameters after cryopreservationen_US
dc.typeArticleen_US

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