A comparative study of bimatoprost and travoprost: Effect on intraocular pressure and ocular circulation in newly diagnosed glaucoma patients

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dc.authorid0000-0002-0184-8033en_US
dc.authorid0000-0002-2572-0376
dc.authorid0000-0001-8305-6600
dc.contributor.authorAlagöz, Gürsoy
dc.contributor.authorGürel, Kamil
dc.contributor.authorBayer, Atilla
dc.contributor.authorSerin, Didem
dc.contributor.authorÇelebi, Serdal
dc.contributor.authorKükner, Şahap
dc.date.accessioned2021-06-23T19:26:00Z
dc.date.available2021-06-23T19:26:00Z
dc.date.issued2008
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractBackground: This study compares intraocular pressure (IOP)-lowering efficacy and retrobulbar hemodynamic effects of bimatoprost and travoprost in patients with newly diagnosed open-angle glaucoma. Methods: Patients were randomly assigned to one of two treatment groups ( bimatoprost group, n = 36; travoprost group, n = 46). IOP levels were measured with Goldmann applanation tonometer. Peak systolic velocity, end-diastolic velocity and resistivity index were obtained for each vessel by color Doppler imaging. Results: Both bimatoprost and travoprost significantly lowered IOP on days 30, 90 and 180 (p < 0.001). There was no significance between the 2 drugs on all follow-up visits. End-diastolic velocity of central retinal artery on day 180 was significantly higher than the value obtained at baseline in both groups. Conclusions: Patients were likely to achieve and maintain low target IOP with both drugs. Both drugs also resulted in improvement in the central retinal artery blood flow. Copyright (c) 2008 S. Karger AG, Basel.en_US
dc.identifier.doi10.1159/000112624
dc.identifier.endpage95en_US
dc.identifier.issn0030-3755
dc.identifier.issn1423-0267
dc.identifier.issue2en_US
dc.identifier.pmid18303228en_US
dc.identifier.scopus2-s2.0-39749165123en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage88en_US
dc.identifier.urihttps://doi.org/10.1159/000112624
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6370
dc.identifier.volume222en_US
dc.identifier.wosWOS:000253400400005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAlagöz, Gürsoy
dc.institutionauthorGürel, Kamil
dc.institutionauthorSerin, Didem
dc.institutionauthorÇelebi, Serdal
dc.institutionauthorKükner, Şahap
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofOphthalmologicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTravoprosten_US
dc.subjectBimatoprosten_US
dc.subjectIntraocular Pressureen_US
dc.subjectOcular Circulationen_US
dc.titleA comparative study of bimatoprost and travoprost: Effect on intraocular pressure and ocular circulation in newly diagnosed glaucoma patientsen_US
dc.typeArticleen_US

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