Case report showed Beau's lines or onychomadesis, not Muehrcke's lines
Yükleniyor...
Dosyalar
Tarih
2016
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Sage Publications Ltd
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
To the Editor,
We wrote for the case report entitled ‘Muehrcke’s lines (Leukonychia striata) due to transretinoic acid therapy for acute promyelocytic leukemia’ presented by Dasanu et al.1 Our assessment is based on clinical photographs submitted by the researchers. It is well known that drug-induced nail abnormalities may result from toxicity to the matrix, the nail bed, or the periungual tissues. The most common symptoms include Beau’s lines, onychomadesis, melanonychia, onycholysis, periungual pyogenic granulomas, and Muehrcke’s lines. Nail changes usually affect several nails and in most cases are asymptomatic. Drugs that most frequently produce nail abnormalities include retinoids, indinavir, and cancer chemotherapeutic agents. In this case, it should be considered all differential diagnosis such as Muehrcke’s lines, Beau’s lines, or onychomadesis occurs due to drugs. In the presented case, we saw transverse white band on her nail plates after receiving 16-week transretinoic acid therapy for acute promyelocytic leukemia. But this cannot identify as a Muehrcke’s line. Because it does not appear the two horizontal white lines that run parallel to the lunula across the width of the nail which are specific for Muehrcke’s lines. Otherwise Muehrcke’s lines are nonpalpable.4 Moreover, we detected broken nail and grooves or furrows on the white nail plate. As a result, these are characteristic of Beau’s lines or onychomadesis not Muehrcke’s lines.
Açıklama
Anahtar Kelimeler
Leukonychia Striata, Transretinoic Acid Therapy, Acute Promyelocytic Leukemia, Beau’s Lines
Kaynak
Journal Of Oncology Pharmacy Practice
WoS Q Değeri
Q3
Scopus Q Değeri
Q3
Cilt
22
Sayı
3
