Hematological parameters and coronary collateral circulation in patients with stable coronary artery disease

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dc.contributor.authorAyhan, Selim
dc.contributor.authorÖztürk, Serkan
dc.contributor.authorErdem, Alim
dc.contributor.authorFatih, Mehmet Fatih
dc.contributor.authorMemioğlu, Tolga
dc.contributor.authorÖzyaşar, Mehmet
dc.contributor.authorYazıcı, Mehmet
dc.date.accessioned2021-06-23T19:34:47Z
dc.date.available2021-06-23T19:34:47Z
dc.date.issued2013
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBACKGROUND: Although hematological parameters have been associated with prognosis in patients with various cardiovascular diseases, their relationship with coronary collateral (CC) circulation in patients with stable coronary artery disease (CAD) is unknown. OBJECTIVE: To investigate the relationship between hematological parameters and CC vessel development in patients with stable CAD. METHODS: A total of 96 patients who underwent coronary angiography were retrospectively enrolled. All study participants had at least one occluded major coronary artery. Development of CCs was classified using the method of Rentrop. Rentrop grades of 0 and 1 indicate poor CCs, whereas grades 2 and 3 indicate good CCs. Hematological parameters, including mean platelet volume (MPV) and neutrophil/lymphocyte (N/L) ratio, were measured. Multivariate logistic regression analysis was performed to identify independent variables. RESULTS: The MPV and N/L ratio were significantly higher in the poor CC group compared with the good CC group. Negative correlations were found in the analyses comparing Rentrop score with MPV and N/L ratio (r=-0.274; P=0.012 and r=-0.339; P=0.001, respectively). In multivariate analysis, the N/L ratio was independently related to CC circulation (OR 0.762 [95% CI 0.587 to 0.988]; P=0.04). CONCLUSION: The results suggest that N/L ratio and MPV are associated with poor CCs, and a high N/L ratio is a significant predictor of poor CC development in patients with stable CAD.en_US
dc.identifier.endpageE15en_US
dc.identifier.issn1205-6626
dc.identifier.issue1en_US
dc.identifier.pmid24294041en_US
dc.identifier.scopus2-s2.0-84878301104en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpageE12en_US
dc.identifier.urihttps://www.webofscience.com/wos/woscc/full-record/WOS:000319219000004
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7623
dc.identifier.volume18en_US
dc.identifier.wosWOS:000319219000004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAyhan, Selim
dc.institutionauthorÖztürk, Serkan
dc.institutionauthorErdem, Alim
dc.institutionauthorFatih, Mehmet
dc.institutionauthorMemioğlu, Tolga
dc.institutionauthorÖzyaşar, Mehmet
dc.institutionauthorYazıcı, Mehmet
dc.language.isoenen_US
dc.publisherPulsus Group Incen_US
dc.relation.ispartofExperimental & Clinical Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCoronary Collateral Circulationen_US
dc.subjectHematological Parametersen_US
dc.subjectMean Platelet Volumeen_US
dc.subjectNeutrophil/lymphocyte Ratioen_US
dc.titleHematological parameters and coronary collateral circulation in patients with stable coronary artery diseaseen_US
dc.typeArticleen_US

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