Are inflammatory parameters an independent predictor of hip osteoarthritis severity? A prospective cross-sectional study

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Küçük Resim

Tarih

2022

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Assoc Medica Brasileira

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

OBJECTIVE: This study aimed to investigate the relationship between the presence of hip osteoarthritis and the neutrophil-lymphocyte ratio, platelet -lymphocyte ratio, monocyte-lymphocyte ratio, and neutrophil-monocyte ratio.METHODS: Participants with hip osteoarthritis and healthy controls aged 45-75 years were recruited in the study. The participants with hip osteoarthritis were divided into two groups: mild/moderate hip osteoarthritis and severe hip osteoarthritis. Complete blood parameters of the participants were recorded, and neutrophil-lymphocyte ratio, neutrophil-monocyte ratio, monocyte-lymphocyte ratio, and platelet-lymphocyte ratio were calculated. Pain severity was evaluated using a visual analog scale.RESULTS: A total of 76 participants with hip osteoarthritis and 59 healthy controls were included in the study. The mean age of the participants was 57.6 +/- 6.11 years. Mean neutrophil-lymphocyte ratio and neutrophil-monocyte ratio values were statistically significantly different between the hip osteoarthritis group and healthy control group (p<0.05). Platelet-lymphocyte ratio, monocyte-lymphocyte ratio, erythrocyte sedimentation rate, and C-reactive protein values were not significantly different between the groups. Also, there was no difference between all inflammatory parameters and hip osteoarthritis severity (p>0.05).CONCLUSIONS: Neutrophil-lymphocyte ratio and neutrophil-monocyte ratio values were higher in patients with hip osteoarthritis than in healthy controls. Mean platelet-lymphocyte ratio, monocyte-lymphocyte ratio, erythrocyte sedimentation rate, and C-reactive protein values did not change according to the presence of hip osteoarthritis. Not all hematological indices give valuable information regarding the severity of hip osteoarthritis.

Açıklama

Anahtar Kelimeler

Hip Osteoarthritis, Inflammation, X-rays, Neutrophil-Lymphocyte Ratio, Knee Osteoarthritis, Disease-Activity

Kaynak

Revista da Associacao Medica Brasileira

WoS Q Değeri

Q4

Scopus Q Değeri

Q3

Cilt

68

Sayı

10

Künye

Korkmaz, M. D., Menekşeoğlu, A. K., & Yakşi, E. (2022). Are inflammatory parameters an independent predictor of hip osteoarthritis severity? A prospective cross-sectional study. Revista da Associação Médica Brasileira, 68, 1423-1427.