Can non-thyroid illness sndrome predict mortality in lung cancer patients? A prospective cohort study

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dc.authorid0000-0001-6013-7330en_US
dc.authorid0000-0002-5078-2958
dc.contributor.authorYaşar, Zehra Aşuk
dc.contributor.authorKıraklı, Cenk
dc.contributor.authorYılmaz, Ufuk
dc.contributor.authorUçar, Zeynep Zeren
dc.contributor.authorTalay, Fahrettin
dc.date.accessioned2021-06-23T19:35:44Z
dc.date.available2021-06-23T19:35:44Z
dc.date.issued2014
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractThis study aims to evaluate the incidence of non-thyroid illness syndrome (NTIS) among patients diagnosed as lung cancer and its association with the stage of the disease, Eastern Cooperative Oncology Group (ECOG) performance score, nutritional parameters, and survival. We enrolled 120 patients that 71 of them with newly diagnosed and staged non-small cell lung cancer and 49 of them small-cell lung cancer. The cases were examined for thyroid function tests, ECOG performance score, and nutritional evaluation before treatment. Also, cases were evaluated for their overall survival rates. NTIS was identified in 30 (42 %) of the 71 non-small cell lung cancer patients and 22 (44 %) of the 49 small-cell lung cancer patients. NTIS was more frequent among advanced stage of cases. Serum albumin level, cholesterol level, lymphocyte level, and body mass index were detected to be significantly low and ECOG performance score was significantly high in cases with NTIS when compared to cases without NTIS. NTIS was found to be negatively correlated with body mass index, ECOG performance score, and serum albumin level, and it was positively correlated with disease stage. NTIS was detected significantly as a poor prognostic factor for lung cancer. NTIS was frequently seen in cases with non-small cell lung cancer and small-cell lung cancer. NTIS can be used as a predictor of poor prognosis for lung cancer patients.en_US
dc.identifier.doi10.1007/s12672-014-0183-0
dc.identifier.endpage246en_US
dc.identifier.issn1868-8497
dc.identifier.issn1868-8500
dc.identifier.issue4en_US
dc.identifier.pmid24832769en_US
dc.identifier.scopus2-s2.0-84904214343en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage240en_US
dc.identifier.urihttps://doi.org/10.1007/s12672-014-0183-0
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7855
dc.identifier.volume5en_US
dc.identifier.wosWOS:000339330800005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorTalay, Fahrettin
dc.institutionauthorYaşar, Zehra Aşuk
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofHormones & Canceren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleCan non-thyroid illness sndrome predict mortality in lung cancer patients? A prospective cohort studyen_US
dc.typeArticleen_US

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