Dating thrombus organization with eosinophil counts in deep venous thrombosis

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dc.authorid0000-0002-6965-7444
dc.authorid0000-0003-2399-9585
dc.authorid0000-0002-1495-1697
dc.authorid0000-0003-3817-851X
dc.contributor.authorMansıroğlu, Aslı Kurtar
dc.contributor.authorSincer, İsa
dc.contributor.authorCoşgun, Mehmet
dc.contributor.authorGüneş, Yılmaz
dc.date.accessioned2021-06-23T18:57:24Z
dc.date.available2021-06-23T18:57:24Z
dc.date.issued2021
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: It is known that eosinophils (EOS) are essential for thrombus formation. Studies have demonstrated the association of EOS with coronary artery disease, stent thrombosis, coronary collateral development, and vasospastic angina. However, there is little data about the association of hemogram parameters, especially EOS counts, with deep venous thrombosis (DVT) subgroups. Methods: The present study comprised 243 patients diagnosed with DVT (of whom 86 were acute, 72 were indeterminate, and 85 were chronic) and 75 control patients. Medical records of all the patients were reviewed, and relevant data were collected retrospectively. The baseline characteristics, as well as hemogram and biochemistry parameters, were recorded. Results: The patients with DVT had significantly lower median EOS count yet higher median neutrophil to lymphocyte ratio (NLR) than those of control patients (P <.001). Similarly, acute DVT patients had lower EOS count yet higher NLR values compared with those of indeterminate and chronic DVT patients. However, EOS count was not significantly different between chronic DVT and control groups. While NLR ratio was significantly correlated with acute DVT (r = 0.34; P <.001), Spearman's correlation test revealed that EOS count was inversely correlated with the presence of acute DVT (r = –0.52; P <.001). Conclusions: Low EOS count may lead the physician to a higher probability of acute DVT rather than indeterminate and chronic DVT.en_US
dc.description.sponsorshipThe editors and reviewers of this article have no relevant financial relationships to disclose per the Journal policy that requires reviewers to decline review of any manuscript for which they may have a conflict of interest.en_US
dc.identifier.doi10.1016/j.jvsv.2020.10.012
dc.identifier.endpage880
dc.identifier.issn2213-333X
dc.identifier.issue4
dc.identifier.pmid33122076en_US
dc.identifier.scopus2-s2.0-85096869229en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage874
dc.identifier.urihttps://doi.org/10.1016/j.jvsv.2020.10.012
dc.identifier.urihttps://hdl.handle.net/20.500.12491/5184
dc.identifier.volume9
dc.identifier.wosWOS:000667721800007en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorMansıroğlu, Aslı Kurtar
dc.institutionauthorSincer, İsa
dc.institutionauthorCoşgun, Mehmet
dc.institutionauthorGüneş, Yılmaz
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofJournal of Vascular Surgery: Venous and Lymphatic Disordersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcuteen_US
dc.subjectChronicen_US
dc.subjectDeep Venous Thrombosisen_US
dc.subjectEosinophilen_US
dc.subjectIndeterminate (Subacute)en_US
dc.titleDating thrombus organization with eosinophil counts in deep venous thrombosisen_US
dc.typeArticleen_US

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