Effect of mitomycin C on endoscopic dacryocystorhinostomy

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dc.authorid0000-0001-9796-0822
dc.contributor.authorApuhan, Tayfun
dc.contributor.authorYıldırım, Yavuz Selim
dc.contributor.authorEroğlu, Faruk
dc.contributor.authorSipahier, Ali
dc.date.accessioned2021-06-23T19:27:34Z
dc.date.available2021-06-23T19:27:34Z
dc.date.issued2011
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: The objectives of the study were to retrospectively analyze the efficacy of intraoperative mitomycin C (MMC) in endoscopic dacryocystorhinostomy (END-DCR) and compare it with external dacryocystorhinostomy (EXT-DCR). Methods: For the comfort of the patients, the procedures were performed under general anesthesia. Intraoperatively during the END-DCR, we applied a cotton pledget soaked in a 0.5 mg/mL solution of MMC for 2.5 minutes. In each patient, a silicone tube was placed into the nasal cavity via the superior and inferior punctae and fixed in the vestibule. We retrospectively analyzed the medical records of patients who underwent END-DCR and EXT-DCR. Results: A retrospective review was performed on the medical records of 43 patients (with a total of 49 affected cases) who were admitted to our clinics with a primary complaint of epiphora. The overall success rates were 91% in END-DCR+MMC and 71.5% in EXT-DCR. Conclusions: Mitomycin C, in appropriate doses, minimizes postoperative granulations and fibrosis. Adjunctive use of MMC is considered to increase the success rate of END-DCR.en_US
dc.identifier.doi10.1097/SCS.0b013e3182319863
dc.identifier.endpage2059en_US
dc.identifier.issn1049-2275
dc.identifier.issue6en_US
dc.identifier.pmid22067858en_US
dc.identifier.scopus2-s2.0-82955226316en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2057en_US
dc.identifier.urihttps://doi.org/10.1097/SCS.0b013e3182319863
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6845
dc.identifier.volume22en_US
dc.identifier.wosWOS:000297741900041en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorApuhan, Tayfun
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofJournal Of Craniofacial Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMitomycin Cen_US
dc.subjectDacryocystorhinostomyen_US
dc.subjectEpiphoraen_US
dc.subjectLacrimalen_US
dc.titleEffect of mitomycin C on endoscopic dacryocystorhinostomyen_US
dc.typeArticleen_US

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