Classifying patients with Behcet's disease for disease severity, using a discriminating analysis method

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dc.authorid0000-0001-9226-5134
dc.contributor.authorPolat, Mualla
dc.contributor.authorVahaboğlu, G.
dc.contributor.authorÖnde, U.
dc.contributor.authorEkşioğlu, M.
dc.date.accessioned2021-06-23T19:26:20Z
dc.date.available2021-06-23T19:26:20Z
dc.date.issued2009
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground. Interleukin (IL)-8 has been shown to correlate with the activity of Behcet's disease (BD). The aim of this study was to develop tools as reliable as IL-8 levels in defining BD severity. Methods. In total, 32 patients with BD and 16 healthy controls were included in the study. Medical history, physical examination, routine laboratory investigations and measurement of serum IL-8 levels were performed. The patients were classified as groups I and II based on the serum IL-8 levels. The patients were then reassigned to groups based on the predictions through discriminating analysis. Results. In addition to the differences between patient and control groups, the differences between groups I and II, group I and controls, and group II and controls were statistically significant. The discriminating analysis results showed that the patients had been assigned to groups I and II with 100% accuracy. Conclusion. Discriminating analysis using clinical and routine laboratory findings indicated that 100% of the patients were accurately assigned to the same groups as their IL-8 levels indicated. This suggests that the classification made according to discriminating analysis using these routine variables is a reliable method in determination of the disease severity.en_US
dc.identifier.doi10.1111/j.1365-2230.2008.02811.x
dc.identifier.endpage155en_US
dc.identifier.issn0307-6938
dc.identifier.issue2en_US
dc.identifier.pmid19187295en_US
dc.identifier.scopus2-s2.0-58549092552en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage151en_US
dc.identifier.urihttps://doi.org/10.1111/j.1365-2230.2008.02811.x
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6510
dc.identifier.volume34en_US
dc.identifier.wosWOS:000262636200005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorPolat, Mualla
dc.language.isoenen_US
dc.publisherWiley-Blackwell Publishing, Incen_US
dc.relation.ispartofClinical And Experimental Dermatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBehcet's Diseaseen_US
dc.titleClassifying patients with Behcet's disease for disease severity, using a discriminating analysis methoden_US
dc.typeArticleen_US

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