C-reactive protein and neutrophil-lymphocyte ratio as predictors of mortality in coronavirus disease 2019
Yükleniyor...
Dosyalar
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
ASSOC MEDICA BRASILEIRA
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
OBJECTIVE: This study investigates whether C-reactive protein, platelet-lymphocyte ratio, and neutrophil-lymphocyte ratio could be useful to predict mortality in COVID-19. METHODS: Data of 635 patients with COVID-19 followed up in Sinop Ataturk State Hospital from February to May 2020 were evaluated retrospectively. Diagnosis of COVID-19 was made according to the interim guidance of the World Health Organization. Patients were grouped into two groups based on mortality as survived and non-survived patients. Age, gender, neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, and C-reactive protein of the groups were investigated and compared. RESULTS: The mean age of the participants was 55.8 +/- 22.3 years. Among the patients, 584 survived and 51 patients died. Age was significantly different between the groups, 54.2 +/- 22.3 in the survived group and 75.6 +/- 11.1 in the dead group (p=0.000). In addition, neutrophil, C-reactive protein, and neutrophil-lymphocyte ratio values were significantly higher in the dead group (p=0.000). platelet-lymphocyte ratio was slightly higher in the dead group, but this difference was not significant (p=0.42). The area under the curve values for age, lymphocyte, platelet, C-reactive protein, and neutrophil-lymphocyte ratio are 0.797, 0.424, 0.485, 0.778, and 0.729, respectively. CONCLUSIONS: Our results showed that neutrophil-lymphocyte ratio and C-reactive protein are significantly higher in patients leading to death and could be effective biomarkers in predicting COVID-19 fatality. Furthermore, C-reactive protein could be used as an independent biomarker to predict death in patients with COVID-19, regardless of gender and age (p=0.000).
Açıklama
Anahtar Kelimeler
COVID-19, C-Reactive Protein, Neutrophil, Lymphocyte, Platelet, Mortality
Kaynak
Revista Da Associacao Medica Brasileira
WoS Q Değeri
Q3
Scopus Q Değeri
N/A
Cilt
67
Sayı
10
Künye
Ergenç, H., Ergenç, Z., Usanmaz, M., & Gozdas, H. T. (2021). C-reactive protein and neutrophil–lymphocyte ratio as predictors of mortality in coronavirus disease 2019. Revista da Associação Médica Brasileira, 67, 1498-1502.
