Effects of artificial ultraviolet C radiation on several blood and urine parameters related to renal and hepatic functions in albino mice

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dc.authorid0000-0002-5148-723Xen_US
dc.authorid0000-0003-3084-125Xen_US
dc.authorid0000-0001-6231-5524en_US
dc.authorid0000-0002-4759-7858en_US
dc.contributor.authorAltınas, Arif
dc.contributor.authorBilgili, Ali
dc.contributor.authorEşsiz, Dinç
dc.contributor.authorÜren, Nilgün
dc.contributor.authorAltıntaş, Levent
dc.contributor.authorPekcan, Mert
dc.contributor.authorTürker, Hüseyin
dc.date.accessioned2021-06-23T19:20:38Z
dc.date.available2021-06-23T19:20:38Z
dc.date.issued2007
dc.departmentBAİBÜ, Mudurnu Süreyya Astarcı Meslek Yüksekokulu, Bitkisel ve Hayvansal Üretim Bölümüen_US
dc.description.abstractThe effects of artificial UVC radiation on some blood and urine parameters related to hepatic and renal functions in mice radiated with 30-watt UVC lamp (254 nm and 0.00014 J/cm(2)/s) were examined. Sixty female mice (Swiss Albino) were used as test animals. The animals were fed a mouse diet and water ad libitum and then exposed to artificial UVC for 8 h daily. Blood and urine samples were taken before radiation (control) and at the 7(th), 15(th), 30(th), 45(th), 60(th), and 75(th) d after radiation exposure. The samples were collected in different pools. Urea, creatinine, cholesterol, ALT, AST, ALP, and GGT levels were determined in serum, and protein electrophoresis was made (SDS-PAGE) in urine samples. Significant increase (P<0.001) in serum urea values were observed on the 15(th) and 30(th) d of the exposure. Urea levels returned to the initial values. Increase in creatinine levels after 7(th) d of exposure and decrease until the 60th d (significant on the 15(th), and 45(th) d) were found. Creatinine levels increased again on the 75(th) d (P<0.001). Serum cholesterol and AST values were significantly increased (P<0.01) during the whole period of the exposure, except the 45(th) d. Serum ALT levels were not significantly affected during 30(th) d exposure. They decreased on the 45(th) d (P<0.01) and then increased on the 75(th) d (P<0.01). Serum GGT and ALP levels were decreased during the whole period of the exposure (P<0.01), and GGT activity was at immeasurable levels on the 30(th), 45(th), and 60(th) d. Proteinuria, determined by microscopic observation Of Urine sediment, and the increase in serum urea and creatinine, observed on the 7(th), and 75(th) d of the exposure, were considered a renal disorder, and according to the electroplioretical pattern Of Urine proteins (SDS-PAGE) were defined as mostly glomerulo-tubular type and glomerular type. This indicates that artificial UVC radiation significantly affected the renal function (P<0.01), while the hepatic functions were affected significantly (P<0.01) just on the 75(th) d of the exposure., Concerning the data, which coincide one on the top of the other, there was the opinion that the kidneys and lk,cr showed different sensitivity to artificial UVC radiation.en_US
dc.identifier.endpage308en_US
dc.identifier.issn0042-4870
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-34547995036en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage303en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6146
dc.identifier.urihttps://www.webofscience.com/wos/woscc/full-record/WOS:000247794900023
dc.identifier.volume51en_US
dc.identifier.wosWOS:000247794900023en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorBilgili, Ali
dc.language.isoenen_US
dc.publisherNatl Veterinary Research Insten_US
dc.relation.ispartofBulletin Of The Veterinary Institute In Pulawyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMiceen_US
dc.subjectUVC-radiationen_US
dc.subjectHepatic functionen_US
dc.subjectRenal functionen_US
dc.subjectUrine proteinsen_US
dc.titleEffects of artificial ultraviolet C radiation on several blood and urine parameters related to renal and hepatic functions in albino miceen_US
dc.typeArticleen_US

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