Does random pattern skin flap supply adequate circulation to the underlying muscle through musculocutaneous perforators by reverse flow? An experimental study

Basit Öğe Kaydı
dc.authorid0000-0002-3045-9942en_US
dc.authorid0000-0001-8838-8262en_US
dc.authorid0000-0003-3937-7174en_US
dc.contributor.authorYazar, Şükrü
dc.contributor.authorÇetinkale, Oğuz
dc.contributor.authorDemir, Mustafa
dc.contributor.authorDemirkesen, Cuyan
dc.contributor.authorArslan, Hakan
dc.date.accessioned2021-06-23T19:20:18Z
dc.date.available2021-06-23T19:20:18Z
dc.date.issued2007
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractAn experimental study was designed to examine whether the blood supply of the muscle would be maintained by a reverse flow from the random pattern skin flap through the musculocutaneous perforators. A flap model containing rat rectus abdominis muscle and randomly based overlying abdominal skin was designed. Sixty rats were divided into four experimental groups as follows. In group I, scintigraphy and microangiography were performed in 10 and 6 rats, respectively, immediately after flap elevation. In group II, scintigraphy and microangiography were performed in 10 and 6 rats, respectively, 2 days after flap elevation. In group III, surviving skin paddle area was evaluated in 16 rats 7 days after flap elevation. After evaluation of surviving skin paddle area, the same animals were used for microangiographic (n¼6) and scintigraphic (n¼10) studies at the same day. In group IV, histopathologic examination was done in six flap muscles each 2 and 6 weeks after flap elevation (n¼12). The mean percentage of surviving skin paddle area was 95.6 6.5% on postoperative day 7. Microangiography showed progressively developed blood flow from the skin to muscle through the musculocutaneous perforators in groups II and III, respectively. The radioisotope uptake of the operated muscle was 40.9 12.8% immediately after flap elevation (group I), 58.3 15.6% on postoperative day 2 (group II), and 70.7 25.6% on postoperative day 7 (group III). There was a significant difference only between group I and group III (p<0.05, analysis of variance). Histopathologically prominent atrophy, lipomatoses, and fibroses were revealed at week 6. The poor circulation and viability outcomes of the muscle revealed in the study are because of immediately insufficient blood microcirculation at the distal part of the random pattern skin flap.en_US
dc.identifier.doi10.1055/s-2007-974651
dc.identifier.endpage161en_US
dc.identifier.issn0743-684X
dc.identifier.issue3en_US
dc.identifier.pmid17479454en_US
dc.identifier.scopus2-s2.0-34247555881en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage155en_US
dc.identifier.urihttps://doi.org/10.1055/s-2007-974651
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6093
dc.identifier.volume23en_US
dc.identifier.wosWOS:000246057200007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorYazar, Şükrü
dc.language.isoenen_US
dc.publisherThieme Medical Publ Incen_US
dc.relation.ispartofJournal Of Reconstructive Microsurgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRandom skin flapen_US
dc.subjectReverse blood flowen_US
dc.subjectMuscle viabilityen_US
dc.titleDoes random pattern skin flap supply adequate circulation to the underlying muscle through musculocutaneous perforators by reverse flow? An experimental studyen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Cerrahi Tıp Bilimleri Bölümü Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu