Diagnostic dilemma of paraneoplastic arthritis: case series

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dc.authorid0000-0002-1730-2991
dc.authorid0000-0002-3073-9098
dc.authorid0000-0002-6712-9269
dc.authorid0000-0002-1201-8836
dc.authorid0000-0003-2544-8648
dc.contributor.authorKısacık, Bünyamin
dc.contributor.authorOnat, Ahmet M.
dc.contributor.authorKaşifoğlu, Timuçin
dc.contributor.authorPehlivan, Yavuz
dc.contributor.authorBes, Cemal
dc.date.accessioned2021-06-23T18:55:12Z
dc.date.available2021-06-23T18:55:12Z
dc.date.issued2014
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractObjectives: Paraneoplastic arthritis (PA) may mimic rheumatic diseases. While presenting the demographic and laboratory features of the patients diagnosed with PA, this study also aims to provide possible appropriate tools to differentiate the PA cases from early rheumatoid arthritis (ERA). Methods: Sixty-five patients with PA (male/female: 43/22) from 15 different rheumatology clinics and 50 consecutive patients with ERA (male/female: 13/37) fulfilling the 2010 American College of Rheumatology (ACR) criteria for the diagnosis if the RA from Gaziantep Rheumatology Early Arthritis Trial (GREAT) as controls who were diagnosed at least 12 months before, were enrolled into study. Results: Mean ages of the patients with PA and ERA were 50.2 ± 15.3, and 42.7 ± 12.3, respectively, and the mean ages of the patients with PA were significantly higher than the ERA. Unlike the ERA patients, in our case series PA was predominantly observed among males. Oligoarthritis was significantly higher in solid tumors in contrast to ERA (P = 0.001). Polyarthritis and symmetric arthritis were significantly higher in the ERA group in contrast to all malignancies (P = 0.001). Rheumatoid factor (RF) and anticyclic citrullinated peptide antibody (anti-CCP) positivity were significantly higher in the ERA group (each P = 0.001). Lactic dehydrogenase levels of hematologic malignancies were significantly higher than other groups (each, P = 0.001). Conclusions: ERA patients had more symmetric joint involvement than PA; laboratory markers could be also an alternative where there is high RF and anti-CCP positivity with antibody levels among the ERA patients. Finally, the demographic features can be used as differentiating factors; ERA was seen predominantly among females aged 40-59 years which refers to young adults.en_US
dc.identifier.doi10.1111/1756-185X.12277
dc.identifier.endpage645en_US
dc.identifier.issn1756-1841
dc.identifier.issue6en_US
dc.identifier.pmid24433553en_US
dc.identifier.scopus2-s2.0-84933520257en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage640en_US
dc.identifier.urihttps://doi.org/10.1111/1756-185X.12277
dc.identifier.urihttps://hdl.handle.net/20.500.12491/4707
dc.identifier.volume17en_US
dc.identifier.wosWOS:000344362300007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorBes, Cemal
dc.language.isoenen_US
dc.publisherBlackwell Publishingen_US
dc.relation.ispartofInternational Journal of Rheumatic Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEarly Rheumatoid Arthritisen_US
dc.subjectMalignancyen_US
dc.subjectParaneoplastic Arthritisen_US
dc.titleDiagnostic dilemma of paraneoplastic arthritis: case seriesen_US
dc.typeArticleen_US

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