Histopathological effects of aloe barbadensis and soybean oil on rat liver

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dc.authorid0000-0002-0334-1658
dc.authorid0000-0001-7965-6229
dc.authorid0000-0001-5064-4195
dc.authorid0000-0001-5824-6159
dc.contributor.authorKosif, Rengin
dc.contributor.authorYılmaz, Fahri
dc.contributor.authorEvrendilek, Gülsün Akdemir
dc.contributor.authorDıramalı, Murat
dc.date.accessioned2021-06-23T19:27:23Z
dc.date.available2021-06-23T19:27:23Z
dc.date.issued2010
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractAloe Barbadensis, which is a species of Aloe Vera, is a popular plant used by the common people and in alternative medicine. This study aimed to analyze the effects of Aloe Barbadensis and soybean oil on liver. For this study Wistar Albino female rats were taken and divided into 3 equal groups; the first group was the control group wherein no treatment was applied, second group in which the dissolved form of A. barbadensis in the soybean oil was applied (25 mg/clay), and the third group which only soybean oil was applied (500 mg/day). Biopsy materials were taken from the lobus dexter of the livers of the rats and analyzed with light microscope after the necessary standard processing of histologic slides. Group I demonstrated normal structural characteristics of rat liver. In Group IT and Group III, we observed nuclear enlargement, mild increase in chromatin and hydropic degeneration and binucleation in some hepatocytes. Liver histology demonstrated congestion in portal veins, sinusoids and the central veins. Merely in Group III, portal venous congestion and in Group II sinusoidal congestion was evident parenchyma of the liver. Additionally in Group III liver histology demonstrated plasmocyte infiltration in portal areas. Our study showed that using soybean with Aloe Barbadensis is synergystic and increasing each others effects. However we didn't observe mononeuclear infiltrations in Group II, these show antinflammatory effects of Aloe Barbadensis. It is determined that, depending on the used dose of Aloe Barbadensis, the toxic effect can change. If Aloe Barbadensis used very high doses it can have toxic effect on hepatocytes.en_US
dc.identifier.endpage1106en_US
dc.identifier.issn0717-9502
dc.identifier.issn0717-9367
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-79952420927en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1101en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6804
dc.identifier.urihttp://dx.doi.org/10.4067/S0717-95022010000400019
dc.identifier.volume28en_US
dc.identifier.wosWOS:000287550900019en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorKosif, Rengin
dc.language.isoenen_US
dc.publisherSoc Chilena Anatomiaen_US
dc.relation.ispartofInternational Journal Of Morphologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAloe Barbadensisen_US
dc.subjectSoybeanen_US
dc.subjectRaten_US
dc.subjectLiveren_US
dc.subjectEffecten_US
dc.titleHistopathological effects of aloe barbadensis and soybean oil on rat liveren_US
dc.typeArticleen_US

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