Comparison of the effect of uric acid/albumin ratio on coronary colleteral circulation with other inflammation-based markers in stable coronary artery disease patients

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dc.authorid0000-0002-3183-5815en_US
dc.authorid0000-0001-8923-8709en_US
dc.authorid0000-0003-0587-3356en_US
dc.authorid0000-0002-4297-1820en_US
dc.authorid0000-0003-1784-3584en_US
dc.authorid0000-0002-2554-0121en_US
dc.contributor.authorMemioğlu, Tolga
dc.contributor.authorToprak, Kenan
dc.contributor.authorYılmaz, Rüstem
dc.contributor.authorKaplangoray, Mustafa
dc.contributor.authorİnanır, Mehmet
dc.contributor.authorAkyol, Selahattin
dc.date.accessioned2024-05-23T07:56:40Z
dc.date.available2024-05-23T07:56:40Z
dc.date.issued2023en_US
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground: The Uric acid/Albumin ratio (UAR) has recently been identified as a prominent marker in cardiovascular diseases. In this study, we aimed to reveal the effect of UAR on coronary collateral circulation (CCC) in patients with stable coronary artery disease (CAD) patients by comparing it with conventional inflammation-based markers.Methods: In this study, 415 consecutive patients who underwent coronary angiography for stable angina pectoris and were found to have chronic total occlusion in at least one coronary artery were retrospectively included. The study population was divided into two groups as good CCC (Rentrop 2-3) and poor CCC (Rentrop 0-1) according to the Rentrop classification, and the groups were compared in terms of UAR and other traditional inflammation-based markers.Results: In the poor CCC group, C-reactive protein/albumin ratio (CAR), monocyte/high-density lipoprotein cholesterol ratio (MHR), neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), systemic immune-inflammation index (SII) and UAR were found to be significantly high (p < .05, for all). UAR negatively correlated with rentrop classification (r = -0.383, p < .001). In multivariate regression analysis, MHR, NLR, SII and UAR were determined as independent predictors for poor CCC (p < .05, for all). The ability of UAR to predict poor CCC was superior to uric acid and albumin alone (p < .0001, for both). In addition, UAR was found to be superior to other inflammation-based markers in predicting poor CCC (p < .005, for all).Conclusion: UAR was identified as a strong and independent predictor of CCC. In this context, UAR may be a useful biomarker in the risk prediction of patients with stable CAD.en_US
dc.identifier.citationToprak, K., Yılmaz, R., Kaplangoray, M., Memioğlu, T., İnanır, M., Akyol, S., ... & Demirbağ, R. (2023). Comparison of the effect of uric acid/albumin ratio on coronary colleteral circulation with other inflammation-based markers in stable coronary artery disease patients. Perfusion, 02676591231202105.en_US
dc.identifier.doi10.1177/02676591231202105
dc.identifier.endpage13en_US
dc.identifier.issn0267-6591
dc.identifier.issn1477-111X
dc.identifier.pmid37674333en_US
dc.identifier.scopus2-s2.0-85170524225en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1en_US
dc.identifier.urihttp://dx.doi.org/10.1177/02676591231202105
dc.identifier.urihttps://hdl.handle.net/20.500.12491/12149
dc.identifier.wosWOS:001063497900001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorMemioğlu, Tolga
dc.institutionauthorİnanır, Mehmet
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofPerfusion-Uken_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectUric Aciden_US
dc.subjectUric Acid/Albumin Ratioen_US
dc.subjectCoronary Collateral Circulationen_US
dc.subjectInflammation-Based Markersen_US
dc.subjectStable Coronary Artery Diseaseen_US
dc.subjectC-Reactive Proteinen_US
dc.titleComparison of the effect of uric acid/albumin ratio on coronary colleteral circulation with other inflammation-based markers in stable coronary artery disease patientsen_US
dc.typeArticleen_US

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