Paratesticular sarcomas: a report of seven cases

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dc.authorid0000-0003-1937-2771en_US
dc.authorid0000-0002-3951-8881
dc.authorid0000-0002-4899-0758
dc.authorid0000-0001-8590-4831
dc.authorid0000-0002-6784-0667
dc.contributor.authorÜnlü, Yaşar
dc.contributor.authorHuq, Gülben Erdem
dc.contributor.authorÖzyalvaçlı, Gülzade
dc.contributor.authorZengin, Mehmet
dc.contributor.authorKoca, Sevim Baykal
dc.date.accessioned2021-06-23T19:42:37Z
dc.date.available2021-06-23T19:42:37Z
dc.date.issued2015
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractPrimary tumors of the paratesticular region are rare, with paratesticular sarcomas constituting a major proportion of these tumors, particularly in the elderly. The paratesticular region consists of mesothelial, various epithelial and mesenchymal cells and may therefore give rise to a number of tumors with various behaviors. Defining the association between the paratesticular mass and the testicle, and differentiation between benign and malignant masses using radiology is challenging, therefore the mass is usually considered to be malignant and radical orchiectomy with high ligation is performed. The present study reports the cases of seven patients with tumors of the paratesticular region and presents the clinical and significant histological features of the tumors. In total, two patients suffered from dedifferentiated liposarcoma (DDLS), two exhibited leiomyosarcoma, two exhibited low-grade fibromyxoid sarcoma and one case of undifferentiated pleomorphic sarcoma was identified. Radical orchiectomy with high ligation was performed in five cases; simple orchiectomy was performed in one case and excisional biopsy was performed in the remaining case. A leiomyosarcomatous and epithelial membrane antigen (EMA) positive whorl pattern was observed during microscopy in the two DDLS cases. Additionally, one of the low-grade fibromyxoid sarcoma patients exhibited pleomorphism and mitosis in focal areas. To the best of our knowledge, the present study is the second time low-grade fibromyxoid sarcoma cases with paratesticular localization have been reported in the literature. Of the seven cases, four patients succumbed to the disease, one patient is living with the disorder and the two cases of DDLS are living without the disease. Paratesticular sarcomas are often aggressive and a multidisciplinary approach is required for the diagnosis and treatment of these tumors.en_US
dc.identifier.doi10.3892/ol.2014.2629
dc.identifier.endpage312en_US
dc.identifier.issn1792-1074
dc.identifier.issn1792-1082
dc.identifier.issue1en_US
dc.identifier.pmid25435981en_US
dc.identifier.scopus2-s2.0-84911437274en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage308en_US
dc.identifier.urihttps://doi.org/10.3892/ol.2014.2629
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8551
dc.identifier.volume9en_US
dc.identifier.wosWOS:000346638300057en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÖzyalvaçlı, Gülzade
dc.language.isoenen_US
dc.publisherSpandidos Publ Ltden_US
dc.relation.ispartofOncology Lettersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectParatestisen_US
dc.subjectSarcomasen_US
dc.subjectDedifferentiated Liposarcomaen_US
dc.subjectFibromyxois Sarcomaen_US
dc.subjectLeiomyosarcomaen_US
dc.subjectSpindle Cell Liposarcomaen_US
dc.subjectPleomorphic Sarcomaen_US
dc.subjectWhorl Patternen_US
dc.titleParatesticular sarcomas: a report of seven casesen_US
dc.typeArticleen_US

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