Mitral annular calcification is associated with pulse wave velocity but not with augmentation index

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dc.contributor.authorDurmuş, İsmet
dc.contributor.authorKaraman, Kayıhan
dc.contributor.authorÖztürk, Serkan
dc.contributor.authorKutlu, Merih
dc.date.accessioned2021-06-23T19:35:08Z
dc.date.available2021-06-23T19:35:08Z
dc.date.issued2013
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: To investigate the possible relationship between mitral annular calcification (MAC) and arterial stiffness. Subjects and Methods: Forty-two patients (mean age 68 8 6 years) with MAC and an age-matched control group of 41 individuals (mean age 66 8 6 years) were studied. Arterial stiffness and wave reflections of the study population were evaluated by using applanation tonometry (SphygmoCor). Aortic pulse wave velocity (PWV) was measured as an index of aortic stiffness. The heart rate-corrected augmentation index (AIx @ 75) was estimated as a composite marker of wave reflections and arterial stiffness. Results: Aortic PWV was significantly higher in patients with MAC (12.2 +/- 2.3 m/s) than in controls (10.1 +/- 1.3 m/s, p = 0.0001). However, AIx @ 75 was similar between the groups (28 +/- 10 vs. 29 +/- 10%, p = 0.59). Multivariate analysis involving the whole population revealed that brachial diastolic blood pressure (beta = 1.87, p = 0.04) and MAC (beta = 0.41, p = 0.0001) were independent determinants of aortic PWV. Conclusion: The data showed that MAC was significantly associated with increased arterial stiffness and that it was an independent determinant of aortic PWV. Copyright (C) 2012 S. Karger AG, Baselen_US
dc.identifier.doi10.1159/000343166
dc.identifier.endpage155en_US
dc.identifier.issn1011-7571
dc.identifier.issn1423-0151
dc.identifier.issue2en_US
dc.identifier.pmid23095238en_US
dc.identifier.scopus2-s2.0-84873722264en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage150en_US
dc.identifier.urihttps://doi.org/10.1159/000343166
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7720
dc.identifier.volume22en_US
dc.identifier.wosWOS:000314751000006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÖztürk, Serkan
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofMedical Principles And Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMitral Annular Calcificationen_US
dc.subjectPulse Wave Velocityen_US
dc.subjectAugmentation Indexen_US
dc.titleMitral annular calcification is associated with pulse wave velocity but not with augmentation indexen_US
dc.typeArticleen_US

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