Controlling Nutritional Status (CONUT) score is a novel marker of type 2 diabetes mellitus and diabetic microvascular complications

Basit Öğe Kaydı
dc.authoridAktas, Gulali/0000-0001-7306-5233
dc.authoridAtak, Burcin Meryem/0000-0003-4201-9757
dc.authoridDuman, Tuba/0000-0002-3836-2125
dc.contributor.authorAktas, Gulali
dc.contributor.authorDuman, Tuba Taslamacioglu
dc.contributor.authorTel, Burcin Atak
dc.date.accessioned2024-09-25T20:00:09Z
dc.date.available2024-09-25T20:00:09Z
dc.date.issued2024
dc.departmentAbant İzzet Baysal Üniversitesien_US
dc.description.abstractObjectives: Type 2 diabetes mellitus (T2DM) and its microvascular complications are characterized by chronic inflammation. The Controlling Nutritional Status (CONUT) score is a tool used to assess nutritional status and is often associated indirectly with inflammatory processes. We aimed to compare the CONUT scores of T2DM patients with those of healthy volunteers and to compare T2DM patients with and without microvascular complications. Methods: Patients diagnosed with T2DM and healthy volunteers (as controls) were included in the study. The CONUT score is calculated using the following formula: serum albumin score + total cholesterol score + total lymphocyte count score. CONUT scores of T2DM patients and healthy controls, as well as those of diabetics with and without microvascular complications, were compared. Results: The CONUT scores of the T2DM and control groups were (1 [0-7]) and (0 [0-2]), respectively (p < 0.001). The sensitivity and specificity of the CONUT score (<1.5 threshold) in detecting T2DM were 43% and 90%, respectively (AUC: 0.67, p < 0.001, 95% CI: 0.64-0.71). Moreover, the CONUT score was an independent risk factor for T2DM (OR: 0.34, p < 0.001, 95% CI: 0.22-0.52). The CONUT score of T2DM patients with microvascular complications (2 [0-7]) was significantly higher than that of T2DM patients without microvascular complications (0 [0-4]) and control subjects (0 [0-2]) (p < 0.001). A CONUT score higher than 1.5 had 83% sensitivity and 92% specificity in detecting T2DM with microvascular complications (AUC: 0.91, p < 0.001, 95% CI: 0.89-0.93). Conclusion: The CONUT score could be useful in detecting diabetic microvascular complications in clinical practice, as it is an inexpensive and easy-to-assess marker.en_US
dc.description.sponsorshipThe abstract of this paper has been presented in 22nd annual European Congress of Internal Medicine in Istanbul, Turkey (March-2024).en_US
dc.identifier.doi10.1080/00325481.2024.2373684
dc.identifier.endpage503en_US
dc.identifier.issn0032-5481
dc.identifier.issn1941-9260
dc.identifier.issue5en_US
dc.identifier.pmid38921178en_US
dc.identifier.scopus2-s2.0-85197420442en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage496en_US
dc.identifier.urihttps://doi.org/10.1080/00325481.2024.2373684
dc.identifier.urihttps://hdl.handle.net/20.500.12491/14102
dc.identifier.volume136en_US
dc.identifier.wosWOS:001258502700001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofPostgraduate Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzYK_20240925en_US
dc.subjectType 2 diabetes mellitusen_US
dc.subjectmicrovascular complicationen_US
dc.subjectCONUT scoreen_US
dc.subjectinflammationen_US
dc.subjectnutritionen_US
dc.titleControlling Nutritional Status (CONUT) score is a novel marker of type 2 diabetes mellitus and diabetic microvascular complicationsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu