Impairment of arterial distensibility in premenopausal women with systemic lupus erythematosus

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dc.authorid0000-0003-1710-7018en_US
dc.authorid0000-0002-0171-2224
dc.contributor.authorYıldız, Mustafa
dc.contributor.authorYıldız, Banu Şahin
dc.contributor.authorSoy, Mehmet
dc.contributor.authorTutkan, Hava
dc.date.accessioned2021-06-23T19:21:01Z
dc.date.available2021-06-23T19:21:01Z
dc.date.issued2008
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground and aim: Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease affecting young women and is associated with increased frequency of atherosclerotic vascular diseases. Pulse wave velocity (PWV) is an index of arterial stiffness and a marker of cardiovascular events. This study aimed to investigate arterial distensibility using carotid-femoral (aortic) PWV measurements in premenopausal women with SLE. Methods: We recruited 24 premenopausal women with SLE (SLE duration: 5.3+/-4.6 years) and 24 age- and sex-matched controls. Aortic PWV was determined by using an automatic device, the Complior Colson (France), which allowed on-line pulse wave recording and automatic calculation of PWV Results: The carotid-femoral PWV (8.98+/-2.05 vs. 8.05+/-0.94 m/s), systolic blood pressure (117.08+/-17.12 vs. 106.87+/-11.96 mmHg), pulse pressure (45.62+/-11.91 vs. 38.33+/-9.04 mmHg), heart rate (81.41+/-9.20 vs. 71.12+/-10.32 beat/min) and serum glucose levels (89.68+/-8.12 vs. 73.80+/-10.72 mg/dl) were significantly higher in premenopausal women with SLE, as compared with control subjects (p=0.04, p=0.02, p=0.02, p=0.001, p <0.001, respectively). We found a significant correlation between PWV and age, body mass index, waist-to-hip ratio, heart rate and blood pressure. Conclusion: Arterial distensibility is decreased in premenopausal women with SLE.en_US
dc.identifier.endpage1199en_US
dc.identifier.issn0022-9032
dc.identifier.issn1897-4279
dc.identifier.issue11en_US
dc.identifier.pmid19105096en_US
dc.identifier.scopus2-s2.0-57149100443en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1194en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6204
dc.identifier.urihttps://journals.viamedica.pl/kardiologia_polska/article/view/80690
dc.identifier.volume66en_US
dc.identifier.wosWOS:000262594100010en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorSoy, Mehmet
dc.language.isoenen_US
dc.publisherVia Medicaen_US
dc.relation.ispartofKardiologia Polskaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPulse Wave Velocityen_US
dc.subjectArterial Stiffnessen_US
dc.subjectSystemic Lupus Erythematosusen_US
dc.subjectInflammationen_US
dc.titleImpairment of arterial distensibility in premenopausal women with systemic lupus erythematosusen_US
dc.typeArticleen_US

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