Surgery is the procedure of choice for the treatment of patients with toxic adenoma in an endemic goitre area

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dc.authorid0000-0001-8083-3835
dc.authorid0000-0002-0317-7181
dc.contributor.authorGürleyik, Emin
dc.contributor.authorPehlivan, Mevlüt
dc.contributor.authorGökpınar, İlyas
dc.date.accessioned2021-06-23T19:18:17Z
dc.date.available2021-06-23T19:18:17Z
dc.date.issued2005
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractPurpose : Toxic adenoma is one of the main causes of hyperthyroidism. We investigated the efficacy of surgery in the treatment of toxic adenoma. Methods : Serum thyroid stimulating hormone (TSH) measurement, ultrasound and scintigraphy of the thyroid were made for diagnostic purpose. The safety of surgery was evaluated by postoperative clinical course of patients. The efficacy of surgery was determined by the function of the remaining thyroid tissue. Results : The incidence of hyperthyroidism was 53% in surgically treated patients with nodular goitre in our iodine deficient region. The cause of thyrotoxicosis was toxic adenoma in 15 patients (14%). Suppressed serum TSH levels indicated the hyperthyroidism in all of 15 patients. Solitary solid adenoma was found by ultrasonographic examination, and solitary autonomous hot nodule by thyroid scintigraphy. Surgical treatment consisted of unilateral total lobectomy. it was the primary treatment in 13 patients. Two patients had surgery as secondary treatment after unsuccessful primary radioactive iodine application. The early postoperative clinical course of all patients was uneventful. Thirteen patients who had surgery as primary treatment had normal thyroid function postoperatively contrary to other two patients who became hypothyroid after having unsuccessful radioiodine therapy, and surgery as the secondary treatment. Conclusions : The incidence of hyperthyroidism and toxic adenoma is high in our surgically treated patients with nodular goitre. The diagnosis of toxic adenoma is not difficult by serum TSH measurements, and ultrasound and nuclear imaging of the thyroid. Surgery is effective and safe, and the treatment of choice for patients with toxic adenoma in order to control radically the hyperthyroidism and to achieve the goal of providing the euthyroid status.en_US
dc.identifier.doi10.1080/00015458.2005.11679739
dc.identifier.endpage377en_US
dc.identifier.issn0001-5458
dc.identifier.issue4en_US
dc.identifier.pmid16184719en_US
dc.identifier.scopus2-s2.0-24644466527en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage373en_US
dc.identifier.urihttps://doi.org/10.1080/00015458.2005.11679739
dc.identifier.urihttps://hdl.handle.net/20.500.12491/5689
dc.identifier.volume105en_US
dc.identifier.wosWOS:000231906000009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorGürleyik, Emin
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofActa Chirurgica Belgicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHyperthyroidismen_US
dc.subjectToxic Adenomaen_US
dc.subjectIodine Deficiencyen_US
dc.titleSurgery is the procedure of choice for the treatment of patients with toxic adenoma in an endemic goitre areaen_US
dc.typeArticleen_US

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