Effect of radiation on endothelial functions in workers exposed to radiation

dc.authorid0000-0002-1495-1697
dc.authorid0000-0003-2399-9585
dc.authorid0000-0003-3817-851X
dc.contributor.authorMansıroğlu, Aslı Kurtar
dc.contributor.authorİsa, Sincer
dc.contributor.authorYılmaz, Güneş
dc.date.accessioned2021-06-23T19:54:06Z
dc.date.available2021-06-23T19:54:06Z
dc.date.issued2020
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractOBJECTIVE: Our aim is to determine whether radiation affects the endothelial function of hospital staff working in the radiation unit for diagnostic and therapeutic purposes. We have evaluated endothelial function with vascular imaging parameters such as flow-mediated dilatation (FMD) and aortic stiffness index (ASI). METHODS: A total of 75 employees, 35 of whom are exposed to radiation due to their profession and 40 as the control group, were included in our single-centered study. Demographic data, FMD, aortic stiffness, and echocardiographic findings of the two groups were compared. RESULTS: There were no significant differences in demographic data. Median FMD values tended to be lower in the radiation exposure group [7.89 (2.17-21.88) vs. 11.69 (5.13-27.27) p=0.09]. The FMD value was significantly lower in the catheter laboratory group than in the radiation-exposed (p=0.034) and control (p=0.012) groups. However, there was no statistically significant difference between the non-catheter lab radiation exposed group and the control group (p=0.804). In addition, there was no statistically significant difference in the ASI value between the groups (p=0.201). CONCLUSION: We have found that FMD is decreased among hospital staff working in radiation-associated areas. This may be an early marker for radiation-induced endothelial dysfunction.en_US
dc.identifier.doi10.1590/1806-9282.66.7.992
dc.identifier.endpage997en_US
dc.identifier.issn1806-9282
dc.identifier.issue7en_US
dc.identifier.pmid32844919en_US
dc.identifier.scopus2-s2.0-85089928615en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage992en_US
dc.identifier.urihttps://doi.org/10.1590/1806-9282.66.7.992
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10416
dc.identifier.volume66en_US
dc.identifier.wosWOS:000562623600026en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorİsa, Sincer
dc.institutionauthorYılmaz, Güneş
dc.institutionauthorMansıroğlu, Aslı Kurtar
dc.language.isoenen_US
dc.publisherAssoc Medica Brasileiraen_US
dc.relation.ispartofRevista Da Associacao Medica Brasileiraen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAortic Stiffnessen_US
dc.subjectFlow-Mediated Dilatationen_US
dc.subjectRadiationen_US
dc.subjectEndothelium, Vascularen_US
dc.subjectOccupational Exposureen_US
dc.subjectRadiation Exposureen_US
dc.titleEffect of radiation on endothelial functions in workers exposed to radiationen_US
dc.typeArticleen_US

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