Obstructive sleep apnea syndrome is associated with metabolic syndrome rather than insulin resistance

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dc.authorid0000-0001-5815-6700
dc.contributor.authorOnat, Altan
dc.contributor.authorHergenç, Gülay
dc.contributor.authorUyarel, Hüseyin
dc.contributor.authorYazıcı, Mehmet
dc.contributor.authorTuncer, Mustafa
dc.contributor.authorDoğan, Yüksel
dc.contributor.authorCan, Günay
dc.date.accessioned2021-06-23T19:20:27Z
dc.date.available2021-06-23T19:20:27Z
dc.date.issued2007
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractThe aim of this study was to investigate crosssectionally the prevalence and covariates of obstructive sleep apnea syndrome (OSAS) and its relationship to metabolic syndrome (MS), insulin resistance (IR), and coronary heart disease (CHD) in a population sample of 1,946 men and women representative of Turkish adults. OSAS was identified when habitual snoring and episodes of apnea were combined with another relevant symptom. MS was diagnosed based on modified criteria of the Adult Treatment Panel III and IR by homeostatic model assessment (HOMA). OSAS was identified in 61 men (6.4%) and 58 women (5.8%), at a similar prevalence, after adjusting for covariates. Among individuals with OSAS, significantly higher odds ratios (ORs), adjusted for age, body mass index (BMI), and waist girth, were observed for MS, hypertension, and prevalent CHD, but not for HOMA or menopause. Significantly higher C-reactive protein existed only in women with OSAS who were also more frequent smokers. In logistic regression models, waist circumference, but not BMI nor hypertension, was significantly associated with OSAS among men. In women, by contrast, current cigarette smoking and hypertension were the significant independent covariates. Regression models controlling for sex, age, and smoking revealed that MS (and not IR per se) was associated significantly with OSAS (OR 1.94) in nondiabetic individuals. To conclude, abdominal rather than overall obesity in men and smoking among women are significant independent determinants of OSAS in Turkish adults. OSAS is associated with MS rather than IR per se. Relatively high prevalence of OSAS is observed in Turkish women in whom it is significantly associated with CHD.en_US
dc.identifier.doi10.1007/s11325-006-0077-7
dc.identifier.endpage30en_US
dc.identifier.issn1520-9512
dc.identifier.issn1522-1709
dc.identifier.issue1en_US
dc.identifier.pmid17061139en_US
dc.identifier.scopus2-s2.0-33947616215en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage23en_US
dc.identifier.urihttps://doi.org/10.1007/s11325-006-0077-7
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6117
dc.identifier.volume11en_US
dc.identifier.wosWOS:000244342500002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorYazıcı, Mehmet
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofSleep And Breathingen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSleep apneaen_US
dc.subjectMetabolic syndromeen_US
dc.subjectObesityen_US
dc.subjectInsulin resistanceen_US
dc.subjectHypertensionen_US
dc.subjectPhysical activityen_US
dc.titleObstructive sleep apnea syndrome is associated with metabolic syndrome rather than insulin resistanceen_US
dc.typeArticleen_US

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