The effects of zoledronic acid on mandibular fracture healing in an osteoporotic model : a stereological study

dc.contributor.authorŞener, İsmail
dc.contributor.authorBereket, Cihan
dc.contributor.authorKöşker, Hüseyin
dc.contributor.authorTürer, Akif
dc.contributor.authorTek, Mustafa
dc.date.accessioned2021-06-23T19:34:25Z
dc.date.available2021-06-23T19:34:25Z
dc.date.issued2013
dc.departmentBAİBÜ, Diş Hekimliği Fakültesi, Ağız Diş ve Çene Cerrahisi Ana Bilim Dalıen_US
dc.description.abstractThe aim of this study was to evaluate the effect of zoledronic acid (ZA) in the ovariectomized rat on mandibular fracture. Corpus osteotomies were performed on the mandible of ovariectomized rats. Miniplates were placed on these rats, which were randomly divided into 4 groups. After 7 days, groups 3 and 4 were injected with 0.1 mg/kg ZA. Groups 1 and 2 were control groups, so they were injected 0.1 mg/kg saline solution. Animals in groups 1 and 3 were killed at 4 weeks, whereas groups 2 and 4 were killed 8 weeks after operation. The new bone volume of the fracture gap was examined stereologically. Although the difference was not statistically significant compared with the other groups (groups 1 and 3), more bone formation was found in ZA-treated groups (groups 2 and 4) (P < 0.05).en_US
dc.identifier.doi10.1097/SCS.0b013e3182997816
dc.identifier.endpage1224en_US
dc.identifier.issn1049-2275
dc.identifier.issn1536-3732
dc.identifier.issue4en_US
dc.identifier.pmid23851773en_US
dc.identifier.scopus2-s2.0-84880893514en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1221en_US
dc.identifier.urihttps://doi.org/10.1097/SCS.0b013e3182997816
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7505
dc.identifier.volume24en_US
dc.identifier.wosWOS:000330129000087en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorTek, Mustafa
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofJournal Of Craniofacial Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOsteoporosisen_US
dc.subjectOvariectomyen_US
dc.subjectMandible Fractureen_US
dc.subjectZoledronic Aciden_US
dc.subjectStereologyen_US
dc.titleThe effects of zoledronic acid on mandibular fracture healing in an osteoporotic model : a stereological studyen_US
dc.typeArticleen_US

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