Mean platelet volume and D-dimer in patients with suspected deep venous thrombosis

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dc.authorid0000-0002-3303-8318en_US
dc.authorid0000-0001-5428-0368
dc.contributor.authorCanan, Arzu
dc.contributor.authorHalıcıoğlu, Sıddıka Sezgin
dc.contributor.authorGürel, Safiye
dc.date.accessioned2021-06-23T19:29:22Z
dc.date.available2021-06-23T19:29:22Z
dc.date.issued2012
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractThe aim of this retrospective study was to evaluate the diagnostic value of mean platelet volume (MPV) and D-dimer for acute deep venous thromboembolism (DVT). Two hundred and fifty six patients who presented to the emergency or cardiovascular surgery department with suspected lower limb DVT were retrospectively recruited. Plasma levels of MPV, platelet count, and D-dimer were obtained and duplex sonography examination was performed for all patients. Eighty four patients had acute DVT which was diagnosed by duplex ultrasonography. MPV was significantly higher in patients with DVT than in those without DVT (p < 0.01). The mean MPV was 7.97 +/- A 17.8 and 7.58 +/- A 0.87 fL in patients with DVT and without DVT, respectively (p < 0.01). D-dimer was significantly higher in patients with DVT (p < 0.01). For all the patients, a positive MPV when the cut-off value was 7.3 fL, had 69.7 % sensitivity and 43.9 % specificity. D-dimer (with a cut-off value of 0.5 mu g/mL) had 82.9 % sensitivity and 32.7 % specificity. In case of combination of MPV and D-dimer, the specificity exceeded (65.9 %) despite the reduction in sensitivity (59.2 %). Elevated MPV was found to be associated with acute DVT and high levels of MPV might increase the specificity of D-dimer for exclusion of DVT.en_US
dc.identifier.doi10.1007/s11239-012-0746-2
dc.identifier.endpage287en_US
dc.identifier.issn0929-5305
dc.identifier.issue2en_US
dc.identifier.pmid22588535en_US
dc.identifier.scopus2-s2.0-84865113481en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage283en_US
dc.identifier.urihttps://doi.org/10.1007/s11239-012-0746-2
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7162
dc.identifier.volume34en_US
dc.identifier.wosWOS:000306427900016en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorCanan, Arzu
dc.institutionauthorHalıcıoğlu, Sıddıka Sezgin
dc.institutionauthorGürel, Safiye
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofJournal Of Thrombosis And Thrombolysisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectD-dimeren_US
dc.subjectDoppleren_US
dc.subjectDeep Venous Thrombosisen_US
dc.subjectMean Platelet Volumeen_US
dc.titleMean platelet volume and D-dimer in patients with suspected deep venous thrombosisen_US
dc.typeArticleen_US

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