Rapid enlargement and recurrence of a preexisting intrasellar craniopharyngioma during the course of two pregnancies - case report

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dc.authorid0000-0003-3769-5873
dc.authorid0000-0002-9403-592X
dc.authorid0000-0003-4881-0603
dc.authorid0000-0001-6142-1085
dc.contributor.authorAydın, Yunus
dc.contributor.authorCan, S. Meltem
dc.contributor.authorGülkılık, Ahmet
dc.contributor.authorTürkmenoğlu, Osman
dc.contributor.authorAlatlı, Canan
dc.contributor.authorZiyal, İbrahim
dc.date.accessioned2021-06-23T19:17:16Z
dc.date.available2021-06-23T19:17:16Z
dc.date.issued1999
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractEnlargement of preexisting pituitary adenomas during pregnancy is well documented, but this phenomenon is unusual for nonendocrine pituitary tumors such as craniopharyngiomas. Only six cases of craniopharyngioma have been reported as presenting during pregnancy. The authors describe a 19-year-old woman who presented with amenorrhea and galactorrhea caused by an intrasellar mass. Seven months later, when she was 20 weeks pregnant, the patient developed sudden visual dysfunction. Emergency transsphenoidal surgery was performed to restore visual function, and the tumor was found to be a craniopharyngioma. The patient had spontaneous labor and delivered a healthy infant at term. The tumor recurred 4 years later, during her second pregnancy, and was again entirely removed via a second transsphenoidal approach. She again had a normal term delivery. During the 5-year follow-up period she has demonstrated no endocrinological or visual dysfunction. Control magnetic resonance images have revealed no recurrence of the tumor. The transsphenoidal approach seems to be the safest procedure to use during pregnancy to achieve an immediate optic nerve decompression and to preserve pituitary function.en_US
dc.identifier.doi10.3171/jns.1999.91.2.0322
dc.identifier.endpage324en_US
dc.identifier.issn0022-3085
dc.identifier.issue2en_US
dc.identifier.pmid10433322en_US
dc.identifier.startpage322en_US
dc.identifier.urihttps://doi.org/10.3171/jns.1999.91.2.0322
dc.identifier.urihttps://hdl.handle.net/20.500.12491/5326
dc.identifier.volume91en_US
dc.identifier.wosWOS:000081681800020en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorZiyal, İbrahim
dc.language.isoenen_US
dc.publisherAmer Assoc Neurological Surgeonsen_US
dc.relation.ispartofJournal Of Neurosurgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCraniopharyngiomaen_US
dc.subjectHyperprolactinemiaen_US
dc.subjectIntrasellar Tumoren_US
dc.subjectPregnancyen_US
dc.subjectRapid Growthen_US
dc.titleRapid enlargement and recurrence of a preexisting intrasellar craniopharyngioma during the course of two pregnancies - case reporten_US
dc.typeArticleen_US

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