Rapid enlargement and recurrence of a preexisting intrasellar craniopharyngioma during the course of two pregnancies - case report
Küçük Resim Yok
Tarih
1999
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Amer Assoc Neurological Surgeons
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Enlargement of preexisting pituitary adenomas during pregnancy is well documented, but this phenomenon is unusual for nonendocrine pituitary tumors such as craniopharyngiomas. Only six cases of craniopharyngioma have been reported as presenting during pregnancy. The authors describe a 19-year-old woman who presented with amenorrhea and galactorrhea caused by an intrasellar mass. Seven months later, when she was 20 weeks pregnant, the patient developed sudden visual dysfunction. Emergency transsphenoidal surgery was performed to restore visual function, and the tumor was found to be a craniopharyngioma. The patient had spontaneous labor and delivered a healthy infant at term. The tumor recurred 4 years later, during her second pregnancy, and was again entirely removed via a second transsphenoidal approach. She again had a normal term delivery. During the 5-year follow-up period she has demonstrated no endocrinological or visual dysfunction. Control magnetic resonance images have revealed no recurrence of the tumor. The transsphenoidal approach seems to be the safest procedure to use during pregnancy to achieve an immediate optic nerve decompression and to preserve pituitary function.
Açıklama
Anahtar Kelimeler
Craniopharyngioma, Hyperprolactinemia, Intrasellar Tumor, Pregnancy, Rapid Growth
Kaynak
Journal Of Neurosurgery
WoS Q Değeri
Q1
Scopus Q Değeri
Cilt
91
Sayı
2
