Neutrophil to lymphocyte ratio as an indicative of diabetic control level in type 2 diabetes mellitus

dc.authorid0000-0001-7306-5233en_US
dc.authorid0000-0002-3836-2125
dc.contributor.authorDuman, Tuba Taslamacıoğlu
dc.contributor.authorAktaş, Gülali
dc.contributor.authorAtak, Burçin Meryem
dc.contributor.authorKoçak, Mehmet Zahid
dc.contributor.authorErkuş, Edip
dc.contributor.authorŞavlı, Haluk
dc.date.accessioned2021-06-23T19:52:05Z
dc.date.available2021-06-23T19:52:05Z
dc.date.issued2019
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground: Type 2 diabetes mellitus is associated with chronic low grade inflammation. One of the novel inflammatory markers is hemogram derived neutrophil to lymphocyte ratio (NLR). Objective: We aimed to compare NLR levels of diabetic subjects and healthy controls and to observe possible correlation between NLR and HbA1c. Methods: Medical data of type 2 diabetic subjects admitted to out-patient clinics of our institution between April to July in 2017 were obtained from database and retrospectively analyzed. Control group was chosen from healthy subjects who visited our institution for a routine check-up. Anthropometric measures, laboratory data, including, HbA1c, NLR were recorded. Results: Median NLR of the type 2 DM group 2.44 (1.9) was significantly elevated when compared to healthy controls (1.5 (0.9), (p<0.001). In addition, a Pearson's correlation test revealed that NLR was strongly correlated with age (r=0.26, p=0.008), fasting plasma glucose (r=0.38, p<0.001), and HbA1c (r=0.49, p<0.001). Conclusion: Elevated NLR in otherwise healthy subjects may be indicative of underlying impaired glucose metabolism and moreover, NLR should be used as a marker of diabetic control level in addition to HbA1c in type 2 diabetic subjects.en_US
dc.identifier.doi10.4314/ahs.v19i1.35
dc.identifier.endpage1606en_US
dc.identifier.issn1680-6905
dc.identifier.issn1729-0503
dc.identifier.issue1en_US
dc.identifier.pmid31148989en_US
dc.identifier.scopus2-s2.0-85065538268en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1602en_US
dc.identifier.urihttps://doi.org/10.4314/ahs.v19i1.35
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10096
dc.identifier.volume19en_US
dc.identifier.wosWOS:000465469000035en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKoçak, Mehmet Zahid
dc.institutionauthorDuman, Tuba Taslamacıoğlu
dc.institutionauthorAktaş, Gülali
dc.institutionauthorŞavlı, Haluk
dc.language.isoenen_US
dc.publisherMakerere Univ, Fac Meden_US
dc.relation.ispartofAfrican Health Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectType 2 Diabetes Mellitusen_US
dc.subjectHbA1cen_US
dc.subjectNeutrophil to Lymphocyte Ratioen_US
dc.subjectInflammationen_US
dc.titleNeutrophil to lymphocyte ratio as an indicative of diabetic control level in type 2 diabetes mellitusen_US
dc.typeArticleen_US

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