Neutrophil to lymphocyte ratio as an indicative of diabetic control level in type 2 diabetes mellitus
dc.authorid | 0000-0001-7306-5233 | en_US |
dc.authorid | 0000-0002-3836-2125 | |
dc.contributor.author | Duman, Tuba Taslamacıoğlu | |
dc.contributor.author | Aktaş, Gülali | |
dc.contributor.author | Atak, Burçin Meryem | |
dc.contributor.author | Koçak, Mehmet Zahid | |
dc.contributor.author | Erkuş, Edip | |
dc.contributor.author | Şavlı, Haluk | |
dc.date.accessioned | 2021-06-23T19:52:05Z | |
dc.date.available | 2021-06-23T19:52:05Z | |
dc.date.issued | 2019 | |
dc.department | BAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü | en_US |
dc.description.abstract | Background: Type 2 diabetes mellitus is associated with chronic low grade inflammation. One of the novel inflammatory markers is hemogram derived neutrophil to lymphocyte ratio (NLR). Objective: We aimed to compare NLR levels of diabetic subjects and healthy controls and to observe possible correlation between NLR and HbA1c. Methods: Medical data of type 2 diabetic subjects admitted to out-patient clinics of our institution between April to July in 2017 were obtained from database and retrospectively analyzed. Control group was chosen from healthy subjects who visited our institution for a routine check-up. Anthropometric measures, laboratory data, including, HbA1c, NLR were recorded. Results: Median NLR of the type 2 DM group 2.44 (1.9) was significantly elevated when compared to healthy controls (1.5 (0.9), (p<0.001). In addition, a Pearson's correlation test revealed that NLR was strongly correlated with age (r=0.26, p=0.008), fasting plasma glucose (r=0.38, p<0.001), and HbA1c (r=0.49, p<0.001). Conclusion: Elevated NLR in otherwise healthy subjects may be indicative of underlying impaired glucose metabolism and moreover, NLR should be used as a marker of diabetic control level in addition to HbA1c in type 2 diabetic subjects. | en_US |
dc.identifier.doi | 10.4314/ahs.v19i1.35 | |
dc.identifier.endpage | 1606 | en_US |
dc.identifier.issn | 1680-6905 | |
dc.identifier.issn | 1729-0503 | |
dc.identifier.issue | 1 | en_US |
dc.identifier.pmid | 31148989 | en_US |
dc.identifier.scopus | 2-s2.0-85065538268 | en_US |
dc.identifier.scopusquality | Q3 | en_US |
dc.identifier.startpage | 1602 | en_US |
dc.identifier.uri | https://doi.org/10.4314/ahs.v19i1.35 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12491/10096 | |
dc.identifier.volume | 19 | en_US |
dc.identifier.wos | WOS:000465469000035 | en_US |
dc.identifier.wosquality | Q4 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.institutionauthor | Koçak, Mehmet Zahid | |
dc.institutionauthor | Duman, Tuba Taslamacıoğlu | |
dc.institutionauthor | Aktaş, Gülali | |
dc.institutionauthor | Şavlı, Haluk | |
dc.language.iso | en | en_US |
dc.publisher | Makerere Univ, Fac Med | en_US |
dc.relation.ispartof | African Health Sciences | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Type 2 Diabetes Mellitus | en_US |
dc.subject | HbA1c | en_US |
dc.subject | Neutrophil to Lymphocyte Ratio | en_US |
dc.subject | Inflammation | en_US |
dc.title | Neutrophil to lymphocyte ratio as an indicative of diabetic control level in type 2 diabetes mellitus | en_US |
dc.type | Article | en_US |
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