Differential value of eosinophil count in acute coronary syndrome among elderly patients

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dc.authorid0000-0003-2399-9585en_US
dc.authorid0000-0001-7306-5233en_US
dc.authorid0000-0003-3817-851X
dc.authorid0000-0002-1495-1697
dc.contributor.authorSincer, İsa
dc.contributor.authorGüneş, Yılmaz
dc.contributor.authorMansıroğlu, Aslı Kurtar
dc.contributor.authorAktaş, Gülali
dc.date.accessioned2021-06-23T19:17:12Z
dc.date.available2021-06-23T19:17:12Z
dc.date.issued2019
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractWe aimed to search eosinophil (EOS) counts in elderly acute coronary syndrome (ACS) subjects and to investigate its value for discrimation between unstable angina pectoris (UAP) and myocardial infarction (MI) [non-ST elevation MI (NSTEMI) or ST elevation MI (STEMI)]. The patients were divided into three groups regarding the diagnosis: patients with UAP (63), with NSTEMI (154), and with STEMI (73). General characteristics such as gender, age, systolic and diastolic blood pressure were obtained from patients' files. Complete blood count and biochemical parameters were measured before coronary angiography. EOS was found significantly higher in UAP (0.134 (0.002-0.746) u/mm(3)) compared to NSTEMI (0.085(0.001-0.601) u/mm(3)) and STEMI (0.020(0.001-0.479) u/mm(3)) groups. Kruskal-Wallis test with Bonferroni-corrected Mann-Whitney U-test revealed that EOS count was significantly different between UAP and NSTEMI (p < .001), UAP and STEMI (p < .001) and NSTEMI and STEMI (p < .001) groups. A receiver operating curve (ROC) analysis revealed that a cut-off >0.083 u/mm(3) EOS value had a sensitivity of 79% and specificity of 57% for determination of ACS as UAP (AUC = 0.686, 95% CI, 0.617-0.755). In the present study, we detected an inverse relationship between the number of blood eosinophil count and the severity of ACS subgroups in elderly patients with higher counts in UAP than MI groups.en_US
dc.identifier.doi10.1080/13685538.2019.1643310
dc.identifier.endpage961
dc.identifier.issn1368-5538
dc.identifier.issue5
dc.identifier.pmid31347431en_US
dc.identifier.scopus2-s2.0-85104779484en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage958
dc.identifier.urihttps://doi.org/10.1080/13685538.2019.1643310
dc.identifier.urihttps://hdl.handle.net/20.500.12491/5289
dc.identifier.volume23
dc.identifier.wosWOS:000479339000001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorSincer, İsa
dc.institutionauthorGüneş, Yılmaz
dc.institutionauthorMansıroğlu, Aslı Kurtar
dc.institutionauthorAktaş, Gülali
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofAging Maleen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcute Coronary Syndromeen_US
dc.subjectElderly Patientsen_US
dc.subjectEosinophil Countsen_US
dc.titleDifferential value of eosinophil count in acute coronary syndrome among elderly patientsen_US
dc.typeArticleen_US

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