Effects of European mistletoe (Viscum album L. subsp album) extracts on activity rhythms of the Syrian hamsters (Mesocricetus auratus)

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dc.authorid0000-0001-9617-6673
dc.contributor.authorKarakaş, Alper
dc.contributor.authorTürker, Arzu Uçar
dc.contributor.authorGündüz, Bülent
dc.date.accessioned2021-06-23T19:26:00Z
dc.date.available2021-06-23T19:26:00Z
dc.date.issued2008
dc.departmentBAİBÜ, Fen Edebiyat Fakültesi, Biyoloji Bölümüen_US
dc.description.abstractAntitumor drugs may have some significant nervous system side-effects such as disrupted sleep, eating and drinking patterns. European Mistletoe has been investigated for many decades for its potential use against cancer. To test the hypothesis that the non-antineoplastic effects of mistletoe might be mediated by the actions on the circadian timing system, we have applied mistletoe extracts and vehicle and have measured locomotor activity, feeding and drinking rhythms under constant darkness. Four groups (vehicle, 20 mg kg(-1) ip injection, 40 mg kg(-1) ip injection and 6 g kg(-1) oral administration) were performed for both heat-treated and freeze-dried extracts. None of the administrations changed the locomotor activity, feeding and drinking rhythms in the groups except for 40 mg kg(-1) freeze-dried injected group. The locomotor activity levels decreased in 40 mg kg(-1) freeze-dried extract injected group. These results suggest that, side-effects of mistletoe on circadian timing system of the Syrian hamster depend on the dose and the preparation method of the extract.en_US
dc.identifier.doi10.1080/14786410701654776
dc.identifier.endpage1006en_US
dc.identifier.issn1478-6419
dc.identifier.issue11en_US
dc.identifier.pmid18629716en_US
dc.identifier.scopus2-s2.0-47949123409en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage996en_US
dc.identifier.urihttps://doi.org/10.1080/14786410701654776
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6367
dc.identifier.volume22en_US
dc.identifier.wosWOS:000257752800012en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKarakaş, Alper
dc.institutionauthorTürker, Arzu Uçar
dc.institutionauthorGündüz, Bülent
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltd.en_US
dc.relation.ispartofNatural Product Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectViscum Albumen_US
dc.subjectMistletoeen_US
dc.subjectRhythmen_US
dc.subjectLocomotor Activityen_US
dc.subjectEatingen_US
dc.subjectDrinkingen_US
dc.titleEffects of European mistletoe (Viscum album L. subsp album) extracts on activity rhythms of the Syrian hamsters (Mesocricetus auratus)en_US
dc.typeArticleen_US

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