Facial motor cortex plasticity in patients with unilateral peripheral facial paralysis

dc.authorid0000-0002-1845-0902en_US
dc.authorid0000-0001-8703-0074
dc.authorid0000-0002-9647-4432
dc.authorid0000-0001-7209-7161
dc.contributor.authorYıldız, Serpil
dc.contributor.authorBademkıran, Fikret
dc.contributor.authorYıldız, Nebil
dc.contributor.authorAydoğdu, İbrahim
dc.contributor.authorUludağ, Burhanettin
dc.date.accessioned2021-06-23T19:20:46Z
dc.date.available2021-06-23T19:20:46Z
dc.date.issued2007
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractHand motor representation area expands towards the area of the perioral facial motor cortex in patients with peripheral facial paralysis (PFP) and in hemifacial spasm cases treated with botulinum toxin. In this current study, we aimed to investigate the changes both in the ipsilateral and contralateral facial motor cortex areas in patients with PFP with transcranial magnetic stimulation (TMS). Thirty healthy individuals and 41 patients with unilateral PFP with partial or total axonal degeneration participated in this study. Motor evoked potentials (MEPs) of perioral muscles elicited by TMS of the intracranial portion of the facial nerve and motor cortex, were recorded. TMS was delivered through a figure-of-eight coil. Mapping of the cortical representation of perioral muscles were also studied in 13 of 41 patients and in 10 of control subjects. Mean amplitude of the intact perioral MEPs elicited by the ipsilateral hemisphere TMS, was significantly higher in patients than the control subjects. There was also a mild enlargement of the mean cortical representation area of intact perioral muscles on both hemispheres though it was not significant. We have concluded that there was a cortical reorganization in the hemisphere contralateral to the paralytic side resulting in an increase at corticofugal output related to intact perioral muscles.en_US
dc.identifier.endpage140en_US
dc.identifier.issn1053-8135
dc.identifier.issn1878-6448
dc.identifier.issue2en_US
dc.identifier.pmid17656839en_US
dc.identifier.scopus2-s2.0-34447632638en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage133en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6167
dc.identifier.urihttps://content.iospress.com/articles/neurorehabilitation/nre00347
dc.identifier.volume22en_US
dc.identifier.wosWOS:000248412600009en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorYıldız, Serpil
dc.institutionauthorYıldız, Nebil
dc.language.isoenen_US
dc.publisherIos Pressen_US
dc.relation.ispartofNeurorehabilitationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPeripheral facial paralysisen_US
dc.subjectPlasticityen_US
dc.subjectMotor cortexen_US
dc.subjectMotor evoked potentialsen_US
dc.subjectMappingen_US
dc.titleFacial motor cortex plasticity in patients with unilateral peripheral facial paralysisen_US
dc.typeArticleen_US

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