Oxidative stress response to different exercise intensity with an automated assay: thiol/disulphide homeostasis

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dc.authorid0000-0003-2784-2980en_US
dc.authorid0000-0002-8212-7149en_US
dc.authorid0000-0001-9447-6322
dc.authorid0000-0002-6891-9916
dc.contributor.authorKayacan, Yıldırım
dc.contributor.authorÇetinkaya, Ayhan
dc.contributor.authorYazar, Hayrullah
dc.contributor.authorMakaracı, Yücel
dc.date.accessioned2021-06-23T19:17:12Z
dc.date.available2021-06-23T19:17:12Z
dc.date.issued2019
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractThe aim of this study was to investigate the effect of different intensity treadmill exercises on the thiol disulphide homeostasis which is a new marker of oxidative stress in rats. Male albino Wistar rats were randomly divided into four groups as follows: control (CNT), low (LEx), moderate (MEx) and high-intensity exercise (HEx) group. Exercise was performed for 4 weeks. Following completion of the experimental protocol, serum total thiol, native thiol and disulphide concentrations were determined using a novel automated measurement method. Additionally, dynamic disulphide status, reduced thiol, oxidised thiol and thiol oxidation reduction percentage ratios were compared among the groups. Disulphide levels were significantly lower in MEx group and highest in CNT group (p = .047). The lowest oxidised thiol and the highest reduced thiol were determined in CNT group (p = .086; p = .083). These findings indicate that moderate-intensity exercise is more effective in reducing oxidative stress than low and high-intensity exercise.en_US
dc.identifier.doi10.1080/13813455.2019.1651868
dc.identifier.endpage508
dc.identifier.issn1381-3455
dc.identifier.issue6
dc.identifier.pmid31409146en_US
dc.identifier.scopus2-s2.0-85070884873en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage504
dc.identifier.urihttps://doi.org/10.1080/13813455.2019.1651868
dc.identifier.urihttps://hdl.handle.net/20.500.12491/5288
dc.identifier.volume127
dc.identifier.wosWOS:000481214300001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÇetinkaya, Ayhan
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofArchives Of Physiology And Biochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectExerciseen_US
dc.subjectThiolen_US
dc.subjectDisulphideen_US
dc.subjectOxidative Stressen_US
dc.titleOxidative stress response to different exercise intensity with an automated assay: thiol/disulphide homeostasisen_US
dc.typeArticleen_US

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