Investigation of phage and molasses interactions for the biocontrol of E. coli O157:H7

Yükleniyor...
Küçük Resim

Tarih

2022

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Canadian Science Publishing

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Resistance to antibiotics is one of the most critical health problems in the world. Therefore, finding new treatment methods to be used as alternatives to antibiotics has become a priority for researchers. Similar to phages, certain products containing antimicrobial components, such as molasses, are widely used to elimi-nate resistant bacteria. Molasses has a strong antimicrobial effect on bacterial cells, and this effect is thought to be due to the breakdown of the cytoplasmic cell membrane and cell proteins of the polyphenols in molas-ses. In the present study, phage-molasses interactions were investigated to examine the effects of concomi-tant use. It was found that molasses samples increased the size of phage plaques by up to 3-fold, and MIC and 1/2 x MIC concentrations of molasses increased the burst size of phages. Although no synergistic effect was found between the phage and molasses, the antimicrobial activities of the components and the effect of mo-lasses on phage activity were demonstrated.

Açıklama

Emine K_ubra Tayyarcan is supported by the 100/2000 doctoral scholarship provided by the Council of Higher Education, Turkey.

Anahtar Kelimeler

Bacteriophage, Phage Therapy, Synergism, Molasses, Edema, Phacoemulsification

Kaynak

Canadian Journal of Microbiology

WoS Q Değeri

Q3

Scopus Q Değeri

Q2

Cilt

68

Sayı

1

Künye

Evran, S., Tayyarcan, E. K., Acar-Soykut, E., Guven, B., Durakli-Velioglu, S., & Boyaci, I. H. (2022). Investigation of phage and molasses interactions for the biocontrol of E. coli O157: H7. Canadian Journal of Microbiology, 68(1), 55-65.