Peyronie's disease: a silent consequence of diabetes mellitus

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dc.authorid0000-0002-7571-5727
dc.authorid0000-0003-0580-2144
dc.authorid0000-0002-5767-4837
dc.contributor.authorTefekli, Ahmet
dc.contributor.authorKandıralı, Engin
dc.contributor.authorErol, Bülent
dc.contributor.authorTunç, Murat
dc.contributor.authorKadıoğlu, Ateş
dc.date.accessioned2021-06-23T19:19:30Z
dc.date.available2021-06-23T19:19:30Z
dc.date.issued2006
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractAim: To investigate the clinical characteristics of patients with Peyronie's disease (PD) and diabetes mellitus (DM). Methods: During an 8-year period, a total of 307 men seen at our outpatient clinic were diagnosed with PD. Clinical characteristics, penile deformities and the erectile status of patients with PD and DM together (n = 102) were retrospectively analyzed and compared to patients with PD alone with no risk factors for systemic vascular diseases (n = 97). Results: The prevalence of PD among men with DM and sexual dysfunction was 10.7%. The mean age of diabetic patients with PD was (55.9 +/- 8.9) years; in the no risk factor group it was (48.5 +/- 9.0) years (P < 0.05). The median duration of DM was 5 years. The majority of diabetic patients with PD (56.0%) presented in the chronic phase (P < 0.05), and they were more likely to have a severe penile deformity (> 60 degrees) than the no risk factor group (P < 0.05). In the diabetic group, the most common presenting symptom was penile curvature (81.4%), followed by a palpable nodule on the shaft of the penis (22.5%) and penile pain with erection (14.7%). A total of 19.6% of patients were not aware of their penile deformities in the diabetic group. Erectile function, provided by history and in response to intracavernosal injection and a stimulation test, was significantly diminished in patients with PD and DM (P < 0.05). Conclusion: DM probably exaggerates the fibrotic process in PD. Diabetic patients with PD have a higher risk of severe deformity and erectile dysfunction (ED). PD seems to be a silent consequence of DM and should be actively sought in diabetic men.en_US
dc.identifier.doi10.1111/j.1745-7262.2006.00099.x
dc.identifier.endpage79en_US
dc.identifier.issn1008-682X
dc.identifier.issn1745-7262
dc.identifier.issue1en_US
dc.identifier.pmid16372122en_US
dc.identifier.scopus2-s2.0-30444458826en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage75en_US
dc.identifier.urihttps://doi.org/10.1111/j.1745-7262.2006.00099.x
dc.identifier.urihttps://hdl.handle.net/20.500.12491/5951
dc.identifier.volume8en_US
dc.identifier.wosWOS:000234608900009en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKandıralı, Engin
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofAsian Journal Of Andrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPeyronie's Diseaseen_US
dc.subjectDiabetes Mellitusen_US
dc.subjectErectile Dysfunctionen_US
dc.subjectPenile Deformityen_US
dc.subjectFibrosisen_US
dc.titlePeyronie's disease: a silent consequence of diabetes mellitusen_US
dc.typeArticleen_US

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