Crispr/cas9-mediated immunity in plants against pathogens
Küçük Resim Yok
Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Caister Academic Press
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Global crop production is highly threatened due to pathogen invasion. The huge quantity of pesticides application, although harmful to the environment and human health, is carried out to prevent the crop losses worldwide, every year. Therefore, understanding the molecular mechanisms of path-ogenicity and plant resistance against pathogens is important. The resistance against pathogens is regulated by three important phytohormones, viz. salicylic acid (SA), jasmonic acid (JA) and ethylene (ET). Here we review the possible role of CRISPR technology to understand the plant pathogenicity by mutating genes responsible for pathogen invasion or up-regulating the phytohormones genes or resistant genes. Thus hormone biosynthesis genes, receptor and feeding genes of pathogens could be important targets for modifications using CRISPR/Cas9 following multiplexing tool box strategy in order to edit multiple genes simultane-ously to produce super plants. Here we put forward our idea that the genes would be either mutated in case of plant receptor protein targets of pathogens or up-regulation of resistant genes or hormone bio-synthesis genes will be better choice for resistance against pathogens. © 2018, Caister Academic Press. All rights reserved.
Açıklama
Anahtar Kelimeler
Animals, Bacteria, Bacterial Proteins, CRISPR-Cas Systems, Crops, Agricultural, Cyclopentanes, Disease Resistance, Endonucleases, Ethylenes, Fungi, Gene Editing, Genome, Plant, Mutation, Nematoda, Oxylipins, Plant Diseases, Plant Growth Regulators, Plant Proteins, Salicylic Acid, bacterial protein, Cas9 endonuclease Streptococcus pyogenes, cyclopentane derivative, endonuclease, ethylene, ethylene derivative, jasmonic acid, oxylipin, phytohormone, plant protein, salicylic acid, animal, bacterium, biosynthesis, CRISPR Cas system, crop, disease resistance, fungus, gene editing, genetics, immunology, metabolism, microbiology, mutation, nematode, parasitology, pathogenicity, plant disease, plant genome, procedures
Kaynak
Current Issues in Molecular Biology
WoS Q Değeri
Scopus Q Değeri
Q2
Cilt
26
