Daily rhythm in serum melatonin and leptin levels in the Syrian hamster (Mesocricetus auratus)

Basit Öğe Kaydı
dc.authorid0000-0003-0497-8287
dc.contributor.authorGündüz, Bülent
dc.date.accessioned2021-06-23T19:17:26Z
dc.date.available2021-06-23T19:17:26Z
dc.date.issued2002
dc.departmentBAİBÜ, Fen Edebiyat Fakültesi, Biyoloji Bölümüen_US
dc.description.abstractMelatonin is produced and secreted by the pineal gland in a rhythmic manner; circulating levels are high at night and low in the day. Leptin is a hormone secreted by adipocytes as a product of the obese gene and plays an important role in regulating body energy homeostasis and reproductive function in rodents and humans. The present study was conducted to examine daily fluctuations in serum levels of melatonin and leptin in Syrian hamster. We measured serum leptin and melatonin levels by ELISA in (a) intact and pinealectomized (pinx) male hamsters kept under long daylight conditions [14 h of light (14L)]; (b) intact and pinx hamsters under short daylight (10L); and (c) intact hamsters in constant light (24L). Blood samples were obtained every 2 h throughout a 24-h period. Statistically significant circadian variations were found in both melatonin and leptin profiles. Their relationship was inverse, i.e. when melatonin was high in the serum, leptin was comparably low. These results suggest that there is a rhythm in leptin levels in the adult male Syrian hamster and this rhythm is pineal gland (melatonin) and/or photoperiod dependent.en_US
dc.identifier.doi10.1016/S1095-6433(02)00041-7
dc.identifier.endpage401en_US
dc.identifier.issn1095-6433
dc.identifier.issue2en_US
dc.identifier.pmid12020655en_US
dc.identifier.scopus2-s2.0-0035999605en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage393en_US
dc.identifier.urihttps://doi.org/10.1016/S1095-6433(02)00041-7
dc.identifier.urihttps://hdl.handle.net/20.500.12491/5409
dc.identifier.volume132en_US
dc.identifier.wosWOS:000176113300015en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorGündüz, Bülent
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofComparative Biochemistry And Physiology A-Molecular & Integrative Physiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMelatoninen_US
dc.subjectLeptinen_US
dc.subjectHamsteren_US
dc.subjectPhotoperioden_US
dc.subjectReproductionen_US
dc.titleDaily rhythm in serum melatonin and leptin levels in the Syrian hamster (Mesocricetus auratus)en_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
bulent-gunduz.pdf
Boyut:
148.87 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam metin/ Full text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Biyoloji Bölümü Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu