Effect of quadrant switch on intraocular pressure change in intravitreal aflibercept or ranibizumab injection applications

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dc.authorid0000-0003-4468-3985en_US
dc.authorid0000-0001-8305-6600en_US
dc.authorid0000-0003-2544-3580en_US
dc.contributor.authorAltıntaş, Melek
dc.contributor.authorUlaş, Fatih
dc.contributor.authorÇelebi, Serdal
dc.contributor.authorUyar, Enes
dc.date.accessioned2024-02-16T07:37:35Z
dc.date.available2024-02-16T07:37:35Z
dc.date.issued2022en_US
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective To evaluate the effect of injection quadrant switch on the intraocular pressure (IOP) change in intravitreal aflibercept or ranibizumab applications. Methods 123 eyes of 123 patients who received intravitreal injection (IVE) into the superotemporal quadrant at least 10 times for age-related macular degeneration or diabetic macular edema have been recruited. The demographic data, lens status, IOP values (preoperative, postoperative 0th min, and postoperative 30th min), and amount of vitreous reflux (VR) following IVE have been recorded. Next IVE application was performed into the inferotemporal quadrant of the patient, which had never been injected before. Results The mean IOP value at postoperative 0th min was 50.24 +/- 7.66 mmHg after injections into the superotemporal quadrant and was 34.85 +/- 4.96 mmHg after injections into the inferotemporal quadrant. No significant difference was observed between the preoperative and postoperative 30th min-IOP values (p > 0.05), while a significant difference was found between the postoperative 0th min-IOP values among quadrants (p < 0.001). VR was significantly higher in applications into the inferotemporal quadrant than those into the superotemporal quadrant (p < 0.001). Conclusion One of the most principal factors affecting the postoperative short-term IOP increase is the amount of VR, and this amount decreases the IOP following an IVE. The high amount of VR produced in the quadrant where the injection was applied for the first time caused a low-level IOP, while the low amount of VR formed in the quadrant where the repeated injections were applied caused a higher IOP.en_US
dc.identifier.citationAltintas, M., Ulas, F., Celebi, S., & Uyar, E. (2022). Effect of quadrant switch on ıntraocular pressure change in ıntravitreal aflibercept or ranibizumab ınjection applications. International Ophthalmology, 42(9), 2841-2846.en_US
dc.identifier.doi10.1007/s10792-022-02274-w
dc.identifier.endpage2846en_US
dc.identifier.issn0165-5701
dc.identifier.issn1573-2630
dc.identifier.issue9en_US
dc.identifier.pmid35357637en_US
dc.identifier.scopus2-s2.0-85127388992en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2841en_US
dc.identifier.urihttp://dx.doi.org/10.1007/s10792-022-02274-w
dc.identifier.urihttps://hdl.handle.net/20.500.12491/12027
dc.identifier.volume42en_US
dc.identifier.wosWOS:000782219600003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorUlaş, Fatih
dc.institutionauthorÇelebi, Serdal
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAflibercepten_US
dc.subjectIntraocular Pressureen_US
dc.subjectIntravitreal Injectionen_US
dc.subjectQuadrant Switchen_US
dc.subjectRanibizumaben_US
dc.subjectVitreous Refluxen_US
dc.titleEffect of quadrant switch on intraocular pressure change in intravitreal aflibercept or ranibizumab injection applicationsen_US
dc.typeArticleen_US

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