Comparison of cerebellar volume between subjects with bilateral congenital blindness and healthy individuals

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dc.authorid0000-0001-8538-8443en_US
dc.authorid0000-0002-0334-1658en_US
dc.authorid0000-0001-5428-0368
dc.contributor.authorKosif, Rengin
dc.contributor.authorŞahin, Bünyamin
dc.contributor.authorGürel, Safiye
dc.date.accessioned2021-06-23T19:34:43Z
dc.date.available2021-06-23T19:34:43Z
dc.date.issued2013
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractCerebellum regulates motor control and physical coordination. It is known that when eye and hand need to be worked in combination, cerebellum is active and it provides coordination between eye and hand. Cerebellar cortex atrophy appears with dismetry and saccadic eye movement. If there is no stimulant related to vision, how cerebellum is adopted under this circumstance? In order to explore this, 27 male and 16 female volunteers with bilateral congenital blindness were compared with 35 male and 33 female healthy volunteers in this study. MR images of cross-sectional sequential cerebellum of volunteers with 1.5 mm thickness were realized in coronal plane. The surface area of apparent cerebellum seen in cross-sections was calculated by using Onis (Ver. 2.1) programme. Surface area data obtained by systematic randomized sampling were converted to volume by Cavalieri method. Cerebellar volume of bilateral congenital blind male was 128.15 +/- 11.11 cm(3), and cerebellar volume of bilateral congenital blind female was 118.60 +/- 10.73 cm(3). Cerebellar volume for healthy men and women were 132.89 +/- 12.51 cm(3) and 125.97 +/- 10.78 cm(3), respectively. It was revealed that cerebellar volume for bilateral congenital blind men was smaller than that of healthy men, but this difference was not significant. On the other hand cerebellar volume of bilateral congenital blind women was significantly smaller than that of healthy women (p<0.05). No asymmetry was detected between right and left side of cerebellum in both bilateral congenital blind and healthy subjects.en_US
dc.identifier.doi10.4067/S0717-95022013000100039
dc.identifier.endpage245en_US
dc.identifier.issn0717-9502
dc.identifier.issn0717-9367
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84878765063en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage239en_US
dc.identifier.urihttps://doi.org/10.4067/S0717-95022013000100039
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7602
dc.identifier.volume31en_US
dc.identifier.wosWOS:000321868400039en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorKosif, Rengin
dc.institutionauthorGürel, Safiye
dc.language.isoenen_US
dc.publisherSoc Chilena Anatomiaen_US
dc.relation.ispartofInternational Journal Of Morphologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBilateral Congenital Blindnessen_US
dc.subjectCerebellumen_US
dc.subjectVolumeen_US
dc.titleComparison of cerebellar volume between subjects with bilateral congenital blindness and healthy individualsen_US
dc.typeArticleen_US

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