Effect of n-butyl-2-cyanoacrylate on the tensile strength and pressure resistance of tracheal anastomoses ex vivo

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dc.contributor.authorBiçer, Yusuf Özgür
dc.contributor.authorKöybaşı, Serap
dc.contributor.authorKazaz, Hasan
dc.contributor.authorSeyhan, Sinan
dc.date.accessioned2021-06-23T19:42:20Z
dc.date.available2021-06-23T19:42:20Z
dc.date.issued2015
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractObjectives To investigate the effects of n-butyl-2-cyanoacrylate on tracheal anastomoses in terms of increased tension and intraluminal pressure ex vivo. Study Design Ex vivo experimental study. Setting Tertiary referral center (Department of Otolaryngology). Subjects and Methods Thirty sheep tracheas were used. Four cartilage rings were resected from the tracheas that were 20 cm in length. End-to-end anastomoses were performed by using Vicryl only (group 1), Vicryl and n-butyl-2-cyanoacrylate (group 2), and n-butyl-2-cyanoacrylate only (group 3). The amount of force to break off the anastomosis and the amount of intraluminal pressure to arouse air leakage through the anastomosis were measured. Results The mean force required to break off was 171.9 29.7 N in group 1, 164.8 +/- 26 N in group 2, and 13.52 +/- 2 N in group 3. The mean force required to break off in group 3 was significantly lower than those in groups 1 and 2 (P = .008 and P = .008, respectively). The mean pressure required to cause air leakage was 49.6 +/- 9.1 mm Hg in group 1, 113 +/- 14.4 mm Hg in group 2, and 15 +/- 4.2 mm Hg in group 3. Group 2 was found to be more resistant to intraluminal pressure than groups 1 and 3 (P = .008 and P = .008, respectively). Conclusion n-Butyl-2-cyanoacrylate had no significant effect on tensile strength. However, its application on the suture line provided extra pressure resistance ex vivo. We believe that further studies need to be conducted to investigate its long-term effects and histological impact on tracheal anastomoses in vivo.en_US
dc.identifier.doi10.1177/0194599814560140
dc.identifier.endpage301en_US
dc.identifier.issn0194-5998
dc.identifier.issn1097-6817
dc.identifier.issue2en_US
dc.identifier.pmid25505258en_US
dc.identifier.scopus2-s2.0-84922253315en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage297en_US
dc.identifier.urihttps://doi.org/10.1177/0194599814560140
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8448
dc.identifier.volume152en_US
dc.identifier.wosWOS:000349468100019en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorBiçer, Yusuf Özgür
dc.institutionauthorKöybaşı, Serap
dc.institutionauthorKazaz, Hasan
dc.institutionauthorSeyhan, Sinan
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofOtolaryngology-Head And Neck Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTracheaen_US
dc.subjectAnastomosisen_US
dc.subjectCyanoacrylateen_US
dc.subjectPressureen_US
dc.titleEffect of n-butyl-2-cyanoacrylate on the tensile strength and pressure resistance of tracheal anastomoses ex vivoen_US
dc.typeArticleen_US

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