Predictive value of neutrophil-lymphocyte ratio for long-term cardiovascular event following coronary artery bypass grafting

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dc.authorid0000-0003-4709-4705
dc.contributor.authorGürbüz, Orçun
dc.contributor.authorKumtepe, Gencehan
dc.contributor.authorÖzkan, Hakan
dc.contributor.authorKaral, İlker Hasan
dc.contributor.authorVelioğlu, Yusuf
dc.contributor.authorErcan, Abdulkadir
dc.contributor.authorYüksel, Ahmet
dc.date.accessioned2021-06-23T19:54:51Z
dc.date.available2021-06-23T19:54:51Z
dc.date.issued2020
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: To investigate the predictive value of preoperative neutrophil-lymphocyte ratio (NLR) for long-term major adverse cardiac and cerebrovascular events (MACCE), which have not yet been well described, in patients undergoing coronary artery bypass grafting (CABG). Methods: The records of 751 consecutive patients who underwent elective CABG between January 2008 and January 2010 were retrospectively enrolled and stratified according to quartiles of preoperative NLR. At 7.8-year follow-up, MACCE was considered as an endpoint. Results: Overall MACCE was 11.6% of all cases. Long-term myocardial infarction, percutaneous coronary intervention, stroke and cardiovascular mortality were found associated with the upper NLR quartile (P<0.001, P<0.001, P=0.005, P<0.001, respectively). In multivariate analysis, NLR on admission remained an independent predictor of long-term MACCE (OR 1.087, 95% CI 1.026-1.151; P=0.004), in all EuroSCORE risk groups (P<0.001; P<0.001; P=0.029). The receiver operating characteristic (ROC) curve analyses revealed an NLR cut-off value of 4.32 predicting MACCE. Conclusion: NLR is a useful and readily available predictive marker of long-term MACCE following CABG, independent of the EuroSCORE.en_US
dc.identifier.doi10.21470/1678-9741-2018-0362
dc.identifier.endpage284en_US
dc.identifier.issn0102-7638
dc.identifier.issn1678-9741
dc.identifier.issue3en_US
dc.identifier.pmid32549098en_US
dc.identifier.scopus2-s2.0-85086235040en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage274en_US
dc.identifier.urihttps://doi.org/10.21470/1678-9741-2018-0362
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10664
dc.identifier.volume35en_US
dc.identifier.wosWOS:000536043300010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorVelioğlu, Yusuf
dc.institutionauthorYüksel, Ahmet
dc.language.isoenen_US
dc.publisherSoc Brasil Cirurgia Cardiovascen_US
dc.relation.ispartofBrazilian Journal Of Cardiovascular Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCoronary Artery Bypassen_US
dc.subjectPercutaneous Coronary Interventionen_US
dc.subjectMyocardial Infarctionen_US
dc.subjectLymphocytesen_US
dc.subjectStrokeen_US
dc.subjectNeutrophilsen_US
dc.titlePredictive value of neutrophil-lymphocyte ratio for long-term cardiovascular event following coronary artery bypass graftingen_US
dc.typeArticleen_US

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