Evaluation and comparison of optical coherence tomography angiography (OCTA) parameters in normal and moderate myopic individuals

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dc.authorid0000-0001-5454-3113
dc.authorid0000-0003-1018-925X
dc.authorid0000-0003-3669-4377
dc.authorid0000-0002-3053-2396
dc.authorid0000-0001-8363-2983
dc.authorid0000-0003-4468-3985
dc.authorid0009-0002-4077-664X
dc.contributor.authorToprak, Güvenç
dc.contributor.authorUlaş, Fatih
dc.contributor.authorKaymaz, Abdulgani
dc.contributor.authorSoydan, Adem
dc.contributor.authorKaplan, Abdulfatih
dc.contributor.authorAlkan, Yunus
dc.contributor.authorÖzdemir, Buse
dc.contributor.authorBayrak, Abdullah
dc.date.accessioned2024-09-25T19:58:54Z
dc.date.available2024-09-25T19:58:54Z
dc.date.issued2024
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü en_US
dc.description.abstractObjective: The objective of this study was to evaluate and compare Optical Coherence Tomography Angiography (OCTA) parameters in patients with moderate myopia and healthy individuals retrospectively. Methods: A total of 80 male individuals aged 18-20 years were included in the study with 40 moderate myopic and 40 healthy persons. All participants underwent detailed ocular examination including refraction, intraocular pressure (IOP), visual acuity, biomicroscopy, OCTA measurement and optic biometry measurement. Retinal, retinal nerve fiber layer and choroidal layer thicknesses were evaluated in mu m with the help of the software available in the OCTA device. Results: The mean axial length (24.32 +/- 0.53 mm) was statistically significantly higher in the moderate myopic group (24.32 mm) compared to the healthy group (23.33 +/- 0.61 mm) (p < 0.001). Spherical equivalent (SE) was found as -3.79 +/- 0.91 D in the moderate myopic group and -0.22 +/- 0.32 D in the healthy group (p < 0.05). The mean superficial foveal mean density (FovSupMVD) and the mean deep foveal mean density (FovDepMVD) were statistically significantly lower in the moderate myopic group than in the healthy group (both, p < 0.001). The mean retinal temporal thickness (RTt) was statistically significantly lower in the moderate myopic group (p = 0.017). There was a mild negative correlation between axial length and FovSupMVD, FovDepMVD in myopes. In axial length ROC analysis, the cutoff value for moderate myopes was found to be 24.15 mm. Mean superficial foveal mean density (FovSupMVD) and mean deep foveal mean density (FovDepMVD), mean retinal temporal thickness (RTt) were significantly lower in the group above 24.15 mm axial length compared to the group below 24.15 mm axial length (all three, p < 0.001). Foveal avascular zone was significantly higher in the group above 24.15 mm axial length (p = 0.016) Conclusion: The results of our study indicate that the mean axial length and spherical equivalent were significantly higher, while retinal temporal thickness, the mean superficial foveal mean density and the mean deep foveal mean density were significantly lower in patients with myopia up to -6.0 D compared to the healthy individuals.en_US
dc.identifier.doi10.1016/j.pdpdt.2024.104077
dc.identifier.issn1572-1000
dc.identifier.issn1873-1597
dc.identifier.pmid38582391en_US
dc.identifier.scopus2-s2.0-85189968439en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1016/j.pdpdt.2024.104077
dc.identifier.urihttps://hdl.handle.net/20.500.12491/13818
dc.identifier.volume46en_US
dc.identifier.wosWOS:001225445900001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorUlaş, Fatih
dc.institutionauthorKaymaz, Abdulgani
dc.institutionauthorSoydan, Adem
dc.institutionauthorKaplan, Abdulfatih
dc.institutionauthorToprak, Güvenç
dc.institutionauthorid0000-0003-4468-3985
dc.institutionauthorid0000-0003-1018-925X
dc.institutionauthorid0000-0002-3053-2396
dc.institutionauthorid0009-0002-4077-664X
dc.institutionauthorid0000-0001-8363-2983
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofPhotodiagnosis and Photodynamic Therapyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzYK_20240925en_US
dc.subjectModerate Myopiaen_US
dc.subjectOptical Coherence Tomography Angiographyen_US
dc.subjectRetinal Vessel Densityen_US
dc.subjectAxial Lengthen_US
dc.subjectOCTen_US
dc.titleEvaluation and comparison of optical coherence tomography angiography (OCTA) parameters in normal and moderate myopic individualsen_US
dc.typeArticleen_US

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