Investigation of the choroidal thickness in patients with hypothyroidism

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dc.authorid0000-0003-4468-3985en_US
dc.authorid0000-0002-8249-2621
dc.authorid0000-0001-9875-6065
dc.contributor.authorUlaş, Fatih
dc.contributor.authorDoğan, Ümit
dc.contributor.authorDikbaş, Oğuz
dc.contributor.authorÇelebi, Serdal
dc.contributor.authorKeleş, Asena
dc.date.accessioned2021-06-23T19:42:17Z
dc.date.available2021-06-23T19:42:17Z
dc.date.issued2015
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractPurpose: The effect of hypothyroidism on the choroidal thickness (CT) was investigated in patients with subclinical hypothyroidism and overt hypothyroidism, and biochemically and clinically euthyroid patients receiving levothyroxine treatment. The patients were compared with healthy subjects. Materials and Methods: One eye of 71 hypothyroid and 22 healthy subjects between 20 and 40 years of age were included in this study. CT measurements were taken at the fovea and at 2 points that were 1500 mu m nasal and temporal to the fovea using spectral-domain optical coherence tomography. Independent sample t-test's and was used for statistical analysis of the data. Results: The CT was significantly thicker in hypothyroid patients compared to healthy subjects (P values were 0.013 for subfoveal, 0.015 for temporal and 0.020 for nasal segments). The intraocular pressure (IOP) and body mass index (BMI) were also significantly higher in hypothyroid patients (P values were 0.021 and 0.003, respectively). There was not a statistically significant difference in the BMI and IOP measurements between healthy subjects and euthyroid patients (P > 0.05). However, there was a statistically significant difference in the subfoveal, temporal and nasal CT measurements between healthy subjects and euthyroid patients (P values were 0.006, 0.031 and 0.013, respectively). Conclusions: All subgroups of hypothyroid patients had thicker CT compared to healthy subjects. Euthyroid patients receiving levothyroxine treatment had lower IOP, BMI levels, and serum lipid levels than patients with subclinical hypothyroidism and overt hypothyroidism.en_US
dc.identifier.doi10.4103/0301-4738.156976
dc.identifier.endpage249en_US
dc.identifier.issn0301-4738
dc.identifier.issn1998-3689
dc.identifier.issue3en_US
dc.identifier.pmid25971170en_US
dc.identifier.scopus2-s2.0-84929577083en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage244en_US
dc.identifier.urihttps://doi.org/10.4103/0301-4738.156976
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8430
dc.identifier.volume63en_US
dc.identifier.wosWOS:000354986100010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorUlaş, Fatih
dc.institutionauthorDoğan, Ümit
dc.institutionauthorDikbaş, Oğuz
dc.institutionauthorÇelebi, Serdal
dc.language.isoenen_US
dc.publisherMedknow Publications & Media Pvt Ltden_US
dc.relation.ispartofIndian Journal Of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChoroidal Thicknessen_US
dc.subjectEnhanced Depth Imagingen_US
dc.subjectHypothyroidismen_US
dc.subjectIntraocular Pressureen_US
dc.subjectOptical Coherence Tomographyen_US
dc.titleInvestigation of the choroidal thickness in patients with hypothyroidismen_US
dc.typeArticleen_US

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