The non-HDL-C/HDL-C ratio is a strong and independent predictor of the no-reflow phenomenon in patients with ST-elevation myocardial infarction

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dc.authorid0000-0002-4297-1820
dc.authorid0000-0001-8923-8709
dc.authorid0000-0002-2554-0121
dc.authorid0000-0002-9008-6631
dc.authorid0000-0002-5574-9436
dc.contributor.authorToprak, Kenan
dc.contributor.authorKaplangöray, Mustafa
dc.contributor.authorAkyol, Selahattin
dc.contributor.authorİnanır, Mehmet
dc.contributor.authorMemioğlu, Tolga
dc.contributor.authorTaşcanov, Mustafa Beğenç
dc.contributor.authorAltıparmak, İbrahim Halil
dc.date.accessioned2024-09-25T19:59:00Z
dc.date.available2024-09-25T19:59:00Z
dc.date.issued2024
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractBackground: No-reflow (NR) is the inability to achieve adequate myocardial perfusion despite successful restoration of attegrade blood flow in the infarct-related artery after primary percutaneous coronary intervention. The non-HDL-C/HDL-C ratio has been shown to be superior to conventional lipid markers in predicting most cardiovascular diseases. In this study, we wanted to reveal the predictive value of the NR by comparing the Non-HDL-C/HDL-C ratio with traditional and non-traditional lipid markers in patients who underwent primary percutaneous coronary intervention (pPCI) due to ST-elevation myocardial infarction (STEMI).Methods: A total of 1284 consecutive patients who underwent pPCI for STEMI were included in this study. Traditional lipid profiles were detected and non-traditional lipid indices were calculated. Patients were classified as groups with and without NR and compared in terms of lipid profiles.Results: No-reflow was seen in 18.8% of the patients. SYNTAX score, maximal stent length, high thrombus burden, atherogenic index of plasma and non-HDL-C/HDL-C ratio were determined as independent predictors for NR (p < 0.05, for all). The non-HDL-C/HDL-C ratio predicts the development of NR in STEMI patients with 71% sensitivity and 67% specificity at the best cut-off value. In ROC curve analysis, the non-HDL-C/HDL-C ratio was superior to traditional and non-traditional lipid markers in predicting NR (p < 0.05, for all).Conclusion: The non-HDL-C/HDL-C ratio can be a strong and independent predictor of NR in STEMI patients and and therefore non-HDL-C/HDL-C ratio may be a useful lipid-based biomarker that can be used in clinical practice to improve the accuracy of risk assessment in patients with STEMI.en_US
dc.identifier.doi10.1080/00015385.2023.2299102
dc.identifier.endpage205en_US
dc.identifier.issn0001-5385
dc.identifier.issn1784-973X
dc.identifier.issue2en_US
dc.identifier.pmid38174719en_US
dc.identifier.scopus2-s2.0-85181449651en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage194en_US
dc.identifier.urihttps://doi.org/10.1080/00015385.2023.2299102
dc.identifier.urihttps://hdl.handle.net/20.500.12491/13863
dc.identifier.volume79en_US
dc.identifier.wosWOS:001136859400001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorİnanir, Mehmet
dc.institutionauthorMemioğlu, Tolga
dc.institutionauthorid0000-0003-1784-3584
dc.institutionauthorid0000-0002-5574-9436
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofActa Cardiologicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzYK_20240925en_US
dc.subjectNon-HDL-C/HDL-C Ratioen_US
dc.subjectST-Elevation Myocardial Infarctionen_US
dc.subjectNon-Traditional Lipidsen_US
dc.subjectNo-Reflow Phenomenonen_US
dc.subjectNon-HDL-C/HDL-C
dc.subjectConventional Lipid Markers
dc.titleThe non-HDL-C/HDL-C ratio is a strong and independent predictor of the no-reflow phenomenon in patients with ST-elevation myocardial infarctionen_US
dc.typeArticleen_US

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