Prophylactic effects of alpha-blockers, Tamsulosin and Alfuzosin, on postoperative urinary retention in male patients undergoing urologic surgery under spinal anaesthesia

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dc.authorid0000-0002-7271-5748en_US
dc.authorid0000-0003-3729-3284en_US
dc.authorid0000-0002-4325-1075
dc.authorid0000-0001-9252-2161
dc.authorid0000-0002-5830-5961
dc.contributor.authorAkkoç, Ali
dc.contributor.authorAydın, Cemil
dc.contributor.authorTopaktaş, Ramazan
dc.contributor.authorKartalmış, Mahir
dc.contributor.authorAltın, Selçuk
dc.contributor.authorMetin, Ahmet
dc.date.accessioned2021-06-23T19:43:35Z
dc.date.available2021-06-23T19:43:35Z
dc.date.issued2016
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractPurpose: Postoperative urinary retention (POUR) is one of the most common complications after surgical procedures under spinal anaesthesia. Recent studies have shown the beneficial effects of alpha-adrenergic blockers in preventing POUR. The aim of this prospective study was to investigate and compare the prophylactic effects of tamsulosin and alfuzosin on POUR after urologic surgical procedures under spinal anaesthesia. Materials and Methods: A total of 180 males who underwent elective urologic surgery were included in this study. The patients were randomly allocated into three Groups. The Group I received placebo. Patients in Group II were given 0.4mg of tamsulosin orally 14 and 2 hours before surgery. Patients in Group III were given 10mg of alfuzosin ER orally 10 and 2 hours before surgery. All patients were closely followed for 24 hours postoperatively and their episodes of urinary retentions were recorded. Results: There were 60 patients in each Group. Their mean age was 35.95 +/- 15.16 years. Fifteen patients in Group I (25%), 3 patients in Group II (5%) and 4 patients in Group III (6.7%) required catheterization because of urinary retention. In tamsulosin group and alfuzosin group, there were a significantly lower proportion of patients with POUR compared with the placebo Group (p=0.002 and p=0.006). The beneficial effects of tamsulosin and alfuzosin on POUR were similar between both Groups (p=0.697). Conclusion: This study suggests that the use of prophylactic tamsulosin or alfuzosin can reduce the incidence of urinary retention and the need for catheterization after urologic surgical procedures under spinal anaesthesia.en_US
dc.identifier.doi10.1590/S1677-5538.IBJU.2015.0256
dc.identifier.endpage584en_US
dc.identifier.issn1677-5538
dc.identifier.issn1677-6119
dc.identifier.issue3en_US
dc.identifier.pmid27286124en_US
dc.identifier.scopus2-s2.0-84978114166en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage578en_US
dc.identifier.urihttps://doi.org/10.1590/S1677-5538.IBJU.2015.0256
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8810
dc.identifier.volume42en_US
dc.identifier.wosWOS:000380066200026en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorMetin, Ahmet
dc.language.isoenen_US
dc.publisherBrazilian Soc Urolen_US
dc.relation.ispartofInternational Braz J Urolen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAdrenergic Alpha-Antagonistsen_US
dc.subjectPostoperative Perioden_US
dc.subjectUrinary Retentionen_US
dc.subjectAnesthesiaen_US
dc.subjectSpinalen_US
dc.titleProphylactic effects of alpha-blockers, Tamsulosin and Alfuzosin, on postoperative urinary retention in male patients undergoing urologic surgery under spinal anaesthesiaen_US
dc.typeArticleen_US

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